FXYD domain-containing ion transport regulator 3 (FXYD3) Recombinant Protein | FXYD3 recombinant protein

Recombinant Human FXYD domain-containing ion transport regulator 3 (FXYD3), partial

Cat. Num. AAA7074335

• Gene Names: FXYD3; MAT8; PLML
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: FXYD domain-containing ion transport regulator 3 (FXYD3); Recombinant Human FXYD domain-containing ion transport regulator 3 (FXYD3); partial; FXYD3 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 21-38aa; Partial
• Sequence: NDLEDKNSPFYYDWHSLQ
• Sequence Length: 61

• Species: Human
• Production Note: Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to [email protected] for more details.
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 209862809
• NCBI GeneID: 5349
• NCBI Accession #: NP_001129479.1
• NCBI GenBank Nucleotide #: NM_001136007.1
• UniProt Accession #: Q14802; Q13211; Q6IB59; A6NDE0; C9JDU2; F5H174; F8WB34
• Molecular Weight: 18.3 kDa
• NCBI Official Full Name: FXYD domain-containing ion transport regulator 3 isoform 3
• NCBI Official Synonym Full Names: FXYD domain containing ion transport regulator 3
• NCBI Official Symbol: FXYD3
• NCBI Official Synonym Symbols: MAT8; PLML
• NCBI Protein Information: FXYD domain-containing ion transport regulator 3
• UniProt Protein Name: FXYD domain-containing ion transport regulator 3
• Protein Family: FXYD domain-containing ion transport regulator
• UniProt Gene Name: FXYD3
• UniProt Synonym Gene Names: MAT8; PLML

NCBI Description

This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]

Uniprot Description

Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na+ out of the cell and K+ into the cell (PubMed:17077088). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (PubMed:21454534). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (PubMed:7836447).