Fucosidase Alpha-L- 1 Plasma Recombinant Protein | FUCA1 recombinant protein
Recombinant Human Fucosidase Alpha-L- 1 Plasma
Gene Names
FUCA1; FUCA
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Fucosidase Alpha-L- 1 Plasma; Recombinant Human Fucosidase Alpha-L- 1 Plasma; FUCA1 Human; Fucosidase Alpha-L- 1 Plasma Human Recombinant; Fucosidase; Alpha-L- 1; Tissue; Alpha-L-Fucoside Fucohydrolase 1; Alpha-L-Fucosidase 1; Alpha-L-Fucosidase I; EC 3.2.1.51; Tissue Alpha-L-Fucosidase; EC 3.2.1; FUCA; Tissue alpha-L-fucosidase; FUCA1 recombinant protein
Host
Sf9 Baculovirus Cells
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
FUCA1 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
VRRAQPPRRY TPDWPSLDSR PLPAWFDEAK FGVFIHWGVF SVPAWGSEWFWWHWQGEGRP QYQRFMRDNY PPGFSYADFG PQFTARFFHP EEWADLFQAA GAKYVVLTTK HHEGFTNWPSPVSWNWNSKD VGPHRDLVGE LGTALRKRNI RYGLYHSLLE WFHPLYLLDK KNGFKTQHFV SAKTMPELYDLVNSYKPDLI WSDGEWECPD TYWNSTNFLS WLYNDSPVKD EVVVNDRWGQ NCSCHHGGYY NCEDKFKPQSLPDHKWEMCT SIDKFSWGYR RDMALSDVTE ESEIISELVQ TVSLGGNYLL NIGPTKDGLI VPIFQERLLAVGKWLSINGE AIYASKPWRV QWEKNTTSVW YTSKGSAVYA IFLHWPENGV LNLESPITTS TTKITMLGIQGDLKWSTDPD KGLFISLPQL PPSAVPAEFA WTIKLTGVKH HHHHH
Sequence Length
466
Related Product Information for FUCA1 recombinant protein
Introduction: Fucosidase Alpha-L- 1 Plasma, also known as FUCA1 is a member of the glycosyl hydrolase 29 family which is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Fucosidosis is an autosomal recessive lysosomal storage disease caused by the absence of alpha-L-fucosidase activity.
Description: FUCA1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 445 amino acids (28-466a.a.) and having a molecular mass of 51.7kDa. (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). FUCA1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Description: FUCA1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 445 amino acids (28-466a.a.) and having a molecular mass of 51.7kDa. (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). FUCA1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Product Categories/Family for FUCA1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,689 Da
NCBI Official Full Name
tissue alpha-L-fucosidase
NCBI Official Synonym Full Names
fucosidase, alpha-L- 1, tissue
NCBI Official Symbol
FUCA1
NCBI Official Synonym Symbols
FUCA
NCBI Protein Information
tissue alpha-L-fucosidase
UniProt Protein Name
Tissue alpha-L-fucosidase
Protein Family
UniProt Gene Name
FUCA1
UniProt Synonym Gene Names
Alpha-L-fucosidase 1
UniProt Entry Name
FUCO_HUMAN
Uniprot Description
FUCA1: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins. Defects in FUCA1 are the cause of fucosidosis (FUCA1D). FUCA1D is an autosomal recessive lysosomal storage disease characterized by accumulation of fucose-containing glycolipids and glycoproteins in various tissues. Clinical signs include facial dysmorphism, dysostosis multiplex, moderate hepatomegaly, severe intellectual deficit, deafness, and according to age, angiokeratomas. Belongs to the glycosyl hydrolase 29 family.
Protein type: EC 3.2.1.51; Glycan Metabolism - other glycan degradation; Hydrolase
Chromosomal Location of Human Ortholog: 1p34
Cellular Component: cytoplasm; lysosomal lumen
Molecular Function: alpha-L-fucosidase activity
Biological Process: fucose metabolic process; glycoside catabolic process
Disease: Fucosidosis
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Product Notes
The FUCA1 fuca1 (Catalog #AAA140720) is a Recombinant Protein produced from Sf9 Baculovirus Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: VRRAQPPRRY TPDWPSLDSR PLPAWFDEAK FGVFIHWGVF SVPAWGSEWF WWHWQGEGRP QYQRFMRDNY PPGFSYADFG PQFTARFFHP EEWADLFQAA GAKYVVLTTK HHEGFTNWPS PVSWNWNSKD VGPHRDLVGE LGTALRKRNI RYGLYHSLLE WFHPLYLLDK KNGFKTQHFV SAKTMPELYD LVNSYKPDLI WSDGEWECPD TYWNSTNFLS WLYNDSPVKD EVVVNDRWGQ NCSCHHGGYY NCEDKFKPQS LPDHKWEMCT SIDKFSWGYR RDMALSDVTE ESEIISELVQ TVSLGGNYLL NIGPTKDGLI VPIFQERLLA VGKWLSINGE AIYASKPWRV QWEKNTTSVW YTSKGSAVYA IFLHWPENGV LNLESPITTS TTKITMLGIQ GDLKWSTDPD KGLFISLPQL PPSAVPAEFA WTIKLTGVK< u>H HHHHH. It is sometimes possible for the material contained within the vial of "Fucosidase Alpha-L- 1 Plasma, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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