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Follicle-stimulating hormone receptor (FSHR) Recombinant Protein | FSHR recombinant protein

Recombinant Sheep Follicle-stimulating hormone receptor (FSHR)

Gene Names
FSHR; FSHRE
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Follicle-stimulating hormone receptor (FSHR); Recombinant Sheep Follicle-stimulating hormone receptor (FSHR); Recombinant Follicle-stimulating hormone receptor (FSHR); Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor; FSHR recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
18-695
Sequence
CHHRLCHCSNGVFLCQDSKVTEMPSDLPRDAVELRFVLTKLRVIPEGAFSGFGDLEKIEISQNDVLEVIEANVFSNLPKLHEIRIEKANNLLYIDPDAFQNLPNLRYLLISNTGIKHLPAVHKIQSLQKVLLDIQDNINIHTVERNSFMGLSFESMIVWLSKNGIQEIHNCAFNGTQLDELNLSDNSNLEELPNDVFQGASGPVILDISRTRIRSLPSYGLENLKKLRAKSTYHLKKLPSLEKFVTLVEASLTYPSHCCAFANWRRQTSDLHPICNKSILRQEVDDMTQARGQRISLAEDDEPSYAKGFDMMYSEFDYDLCSEVVDVTCSPEPDAFNPCEDIMGYDILRVLIWFISILAITGNILVLVILITSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDVHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLECKVHVRHAASIMLVGWVFAFAVALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVLAFVVICGCYTHIYLTVRNPNITSSSSDTKIAKRMAMLIFTDFLCMAPISFFAISASLKVPLITVSKSKILLVLFYPINSCANPFLYAIFTRNFRRDFFILLSKFGCYEVQAQTYRSETSFTAHNFHPRNGHCPPAPRVTNGSNYTLIPLRHLAKN
Sequence Length
695
Species
Ovis aries (Sheep)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
78,238 Da
NCBI Official Full Name
follicle-stimulating hormone receptor
NCBI Official Symbol
FSHR
NCBI Official Synonym Symbols
FSHRE
NCBI Protein Information
follicle-stimulating hormone receptor; FSH-R; follitropin receptor
UniProt Protein Name
Follicle-stimulating hormone receptor
UniProt Gene Name
FSHR
UniProt Synonym Gene Names
FSH-R
UniProt Entry Name
FSHR_SHEEP

Uniprot Description

Function: Receptor for follicle-stimulating hormone. The activity of isoform FSH-R1 is mediated by G proteins which activate adenylate cyclase. Isoform FSH-R2 and isoform FSH-R3 also bind FSH, but this does not result in activation of adenylate cyclase. Isoform FSH-R3 may be involved in calcium signaling.

Subunit structure: Interacts with ARRB2

By similarity.

Subcellular location: Isoform FSH-R1: Cell membrane; Multi-pass membrane protein. Isoform FSH-R2: Cell membrane; Multi-pass membrane protein. Isoform FSH-R3: Cell surface.

Tissue specificity: Isoform FSH-R3 is expressed in ovary and testis, but not in kidney.

Post-translational modification: N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone

By similarity.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.Contains 9 LRR (leucine-rich) repeats.Contains 1 LRRNT domain.

Research Articles on FSHR

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Product Notes

The FSHR fshr (Catalog #AAA954791) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 18-695. The amino acid sequence is listed below: CHHRLCHCSN GVFLCQDSKV TEMPSDLPRD AVELRFVLTK LRVIPEGAFS GFGDLEKIEI SQNDVLEVIE ANVFSNLPKL HEIRIEKANN LLYIDPDAFQ NLPNLRYLLI SNTGIKHLPA VHKIQSLQKV LLDIQDNINI HTVERNSFMG LSFESMIVWL SKNGIQEIHN CAFNGTQLDE LNLSDNSNLE ELPNDVFQGA SGPVILDISR TRIRSLPSYG LENLKKLRAK STYHLKKLPS LEKFVTLVEA SLTYPSHCCA FANWRRQTSD LHPICNKSIL RQEVDDMTQA RGQRISLAED DEPSYAKGFD MMYSEFDYDL CSEVVDVTCS PEPDAFNPCE DIMGYDILRV LIWFISILAI TGNILVLVIL ITSQYKLTVP RFLMCNLAFA DLCIGIYLLL IASVDVHTKS QYHNYAIDWQ TGAGCDAAGF FTVFASELSV YTLTAITLER WHTITHAMQL ECKVHVRHAA SIMLVGWVFA FAVALFPIFG ISSYMKVSIC LPMDIDSPLS QLYVMSLLVL NVLAFVVICG CYTHIYLTVR NPNITSSSSD TKIAKRMAML IFTDFLCMAP ISFFAISASL KVPLITVSKS KILLVLFYPI NSCANPFLYA IFTRNFRRDF FILLSKFGCY EVQAQTYRSE TSFTAHNFHP RNGHCPPAPR VTNGSNYTLI PLRHLAKN. It is sometimes possible for the material contained within the vial of "Follicle-stimulating hormone receptor (FSHR), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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