FRK recombinant protein
FRK protein
Purity
FRK protein was purified using a a proprietary chromatographic technique.
Synonyms
FRK; FRK protein; Fyn-related kinase protein; FRK recombinant protein
Host
Human
Purity/Purification
FRK protein was purified using a a proprietary chromatographic technique.
Form/Format
Supplied in a storage buffer consisting of 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF and 25% glycerol
Sequence Length
308
Protein Type
Recombinant
Biological Significance
FRK or Rak is a nuclear tyrosine kinase and member of the Src sub-family. Restricted expression of FRK is detected in a broad range of cell lines with highest levels in epithelial cells. Increased expression of FRK has been shown in breast and renal cell carcinoma cell lines. In addition the retinoblastoma tumor susceptibility gene product pRb associates with FRK in vitro and in vivo. Overexpression of FRK in beta-cells from the pancreas increases the susceptibility of these cells to beta-cell-toxic events.
Expression System
Sf-9 insect cells
Preparation and Storage
Store at -80 degree C
Related Product Information for FRK recombinant protein
Purified recombinant Human FRK protein
Product Categories/Family for FRK recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
60 kDa
NCBI Official Full Name
Frk
UniProt Protein Name
Frk
Protein Family
UniProt Gene Name
frk
UniProt Entry Name
A4GW43_RHILT
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Product Notes
The FRK frk (Catalog #AAA5304551) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "FRK, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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