Human forkhead box H1 ELISA Kit | FOXH1 elisa kit
Human Forkhead box protein H1, FOXH1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 protein binds SMAD2 and activates an activin response element via binding the DNA motif TGT(G/T)(T/G)ATT. [provided by RefSeq, Jul 2008]
Uniprot Description
FOXH1: Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
Protein type: DNA-binding; Transcription factor; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: nucleoplasm; transcription factor complex; nuclear chromatin; nucleus
Molecular Function: protein domain specific binding; protein binding; androgen receptor binding; DNA binding; sequence-specific DNA binding; bHLH transcription factor binding; SMAD binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; axial mesoderm development; embryonic heart tube anterior/posterior pattern formation; transforming growth factor beta receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; heart looping; negative regulation of estrogen receptor signaling pathway
Disease: Holoprosencephaly 1
Research Articles on FOXH1
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Product Notes
The Human FOXH1 foxh1 (Catalog #AAA9319193) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319193 ELISA Kit recognizes Human FOXH1. It is sometimes possible for the material contained within the vial of "forkhead box H1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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