Human flavin containing monooxygenase 5 ELISA Kit | FMO5 elisa kit

Human Dimethylaniline monooxygenase [N-oxide-forming] 5, FMO5 ELISA Kit

Cat. Num. AAA9330891

• Reactivity: Human
• Synonyms: flavin containing monooxygenase 5; Human Dimethylaniline monooxygenase [N-oxide-forming] 5; FMO5 ELISA Kit; Human Dimethylaniline monooxygenase [N-oxide-forming] 5 (FMO5) ELISA kit; RP11-337C18.2; ; FMO5 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Mouse Body Fluids, Tissue Homogenates, Secretions Or Feces Samples
• Assay Type: Quantitative Sandwich
• Detection Range: 15.6 ng/ml-500 ng/ml
• Sensitivity: 2.0 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for FMO5 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of FMET (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 221316674
• NCBI GeneID: 2330
• NCBI Accession #: NP_001138301.1
• NCBI GenBank Nucleotide #: NM_001144829.2
• UniProt Accession #: P49326; Q8IV22; B2RBG1; C9JJD1
• Molecular Weight: 60,221 Da
• NCBI Official Full Name: dimethylaniline monooxygenase
• NCBI Official Synonym Full Names: flavin containing monooxygenase 5
• NCBI Official Symbol: FMO5
• NCBI Protein Information: dimethylaniline monooxygenase [N-oxide-forming] 5; dimethylaniline monooxygenase [N-oxide-forming] 5; FMO 5; dimethylaniline oxidase 5; hepatic flavin-containing monooxygenase 5
• UniProt Protein Name: Dimethylaniline monooxygenase [N-oxide-forming] 5
• Protein Family: Dimethylaniline monooxygenase
• UniProt Gene Name: FMO5
• UniProt Synonym Gene Names: FMO 5
• UniProt Entry Name: FMO5_HUMAN

NCBI Description

Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

Uniprot Description

FMO5: In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme. Belongs to the FMO family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.14.13.8; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450

Chromosomal Location of Human Ortholog: 1q21.1

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: FAD binding; NADP binding; flavin-containing monooxygenase activity