MADS-box protein FLOWERING LOCUS C (FLC) Recombinant Protein | FLC recombinant protein
Recombinant Arabidopsis thaliana MADS-box protein FLOWERING LOCUS C (FLC)
NCBI and Uniprot Product Information
NCBI Description
MADS-box protein encoded by FLOWERING LOCUS C - transcription factor that functions as a repressor of floral transition and contributes to temperature compensation of the circadian clock. Expression is downregulated during cold treatment. Vernalization, FRI and the autonomous pathway all influence the state of FLC chromatin. Both maternal and paternal alleles are reset by vernalization, but their earliest activation differs in timing and location. Histone H3 trimethylation at lysine 4 and histone acetylation are associated with active FLC expression, whereas histone deacetylation and histone H3 dimethylation at lysines 9 and 27 are involved in FLC repression. Expression is also repressed by two small RNAs (30- and 24-nt) complementary to the FLC sense strand 3? to the polyA site. The small RNAs are most likely derived from an antisense transcript of FLC. Interacts with SOC1 and FT chromatin in vivo. Member of a protein complex.
Uniprot Description
Putative transcription factor that seems to play a central role in the regulation of flowering time in the late-flowering phenotype by interacting with 'FRIGIDA', the autonomous and the vernalization flowering pathways. Inhibits flowering by repressing 'SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1'.
Research Articles on FLC
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Product Notes
The FLC flc (Catalog #AAA1332826) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-196, Full length protein. The amino acid sequence is listed below: MGRKKLEIKR IENKSSRQVT FSKRRNGLIE KARQLSVLCD ASVALLVVSA SGKLYSFSSG DNLVKILDRY GKQHADDLKA LDHQSKALNY GSHYELLELV DSKLVGSNVK NVSIDALVQL EEHLETALSV TRAKKTELML KLVENLKEKE KMLKEENQVL ASQMENNHHV GAEAEMEMSP AGQISDNLPV TLPLLN. It is sometimes possible for the material contained within the vial of "MADS-box protein FLOWERING LOCUS C (FLC), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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