FK506 Binding Protein Like Protein Recombinant Protein | FKBPL recombinant protein

Recombinant FK506 Binding Protein Like Protein (FKBPL)

Cat. Num. AAA2029778

• Gene Names: FKBPL; NG7; DIR1; FKBP4; WISP39
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >95%
• Synonyms: FK506 Binding Protein Like Protein; Recombinant FK506 Binding Protein Like Protein (FKBPL); FKBPL recombinant protein

• Host: Host: E Coli; Source: Prokaryotic expression
• Purity/Purification: >95%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.; MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- METPPVNTIG EKDTSQPQQE WEKNLRENLD SVIQIRQQPR DPPTETLELE VSPDPASQIL EHTQGAEKLV AELEGDSHKS HGSTSQMPEA LQASDLWYCP DGSFVKKIVI RGHGLDKPKL GSCCRVLALG FPFGSGPPEG WTELTMGVGP WREETWGELI EKCLESMCQG EEAELQLPGH SGPPVRLTLA SFTQGRDSWE LETSEKEALA REERARGTEL FRAGNPEGAA RCYGRALRLL LTLPPPGPPE RTVLHANLAA CQLLLGQPQL AAQSCDRVLE REPGHLKALY RRGVAQAALG NLEKATADLKKVLAIDPKNR AAQEELGKVV IQGKNQDAGL AQGLRKMFG
• Sequence Length: 349

• Applicable Applications for FKBPL recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Predicted Molecular Mass: 42.0kDa
• Accurate Molecular Mass (KD): 45kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Tag: N-terminal His-Tag, T7 tag
• Organism Species: Homo sapiens (Human)
• Fragment: Ala432~Ala780
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 119623992
• NCBI GeneID: 63943
• Molecular Weight: 38,176 Da
• NCBI Official Full Name: FK506 binding protein like, isoform CRA_a
• NCBI Official Synonym Full Names: FK506 binding protein like
• NCBI Official Symbol: FKBPL
• NCBI Official Synonym Symbols: NG7; DIR1; FKBP4; WISP39
• NCBI Protein Information: FK506-binding protein-like
• UniProt Protein Name: FK506-binding protein-like
• Protein Family: FK506-binding protein
• UniProt Gene Name: FKBPL
• UniProt Synonym Gene Names: DIR1; NG7; WISp39
• UniProt Entry Name: FKBPL_HUMAN

NCBI Description

The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008]

Uniprot Description

FKBPL: May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: endoplasmic reticulum membrane

Molecular Function: protein binding; FK506 binding; peptidyl-prolyl cis-trans isomerase activity

Biological Process: response to radiation; protein peptidyl-prolyl isomerization