Fish Splicing Factor, Proline- and Glutamine-Rich (SFPQ) ELISA Kit | SFPQ elisa kit
Fish Splicing Factor, Proline- and Glutamine-Rich (SFPQ) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PSF: a proline-and glutamine-rich splicing factor. Essential pre-mRNA splicing factor required early in spliceosome formation. Seems to also bind DNA. The active complex is a heterotetramer of two 52 kDa and two 100 kDa subunits. Reported to be a PKC-alpha-binding protein in the cell nucleus. Two alternatively spliced isoforms have been described.
Protein type: Nuclear receptor co-regulator; RNA splicing; RNA-binding
Chromosomal Location of Human Ortholog: 1p34.3
Cellular Component: chromatin; cytoplasm; extracellular matrix; nuclear matrix; nuclear speck; nucleoplasm; nucleus; paraspeckles; RNA polymerase II transcription factor complex
Molecular Function: chromatin binding; DNA binding; histone deacetylase binding; protein binding; protein homodimerization activity; RNA binding; transcription regulatory region DNA binding
Biological Process: activation of innate immune response; alternative mRNA splicing, via spliceosome; double-strand break repair via homologous recombination; innate immune response; mRNA processing; negative regulation of circadian rhythm; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; positive regulation of sister chromatid cohesion; positive regulation of transcription from RNA polymerase II promoter; regulation of circadian rhythm; rhythmic process; RNA splicing; transcription, DNA-dependent
Research Articles on SFPQ
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Product Notes
The Fish SFPQ sfpq (Catalog #AAA9399955) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9399955 ELISA Kit recognizes Fish SFPQ. It is sometimes possible for the material contained within the vial of "Splicing Factor, Proline- and Glutamine-Rich (SFPQ), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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