Fish Rap Guanine Nucleotide Exchange Factor 3 (RAPGEF3) ELISA Kit | RAPGEF3 elisa kit

Fish Rap Guanine Nucleotide Exchange Factor 3 (RAPGEF3) ELISA Kit

• Gene Names: Rapgef3; Epac
• Reactivity: Fish
• Synonyms: Rap Guanine Nucleotide Exchange Factor 3 (RAPGEF3); Fish Rap Guanine Nucleotide Exchange Factor 3 (RAPGEF3) ELISA Kit; RAPGEF3 elisa kit

• Reactivity: Fish
• Sequence Length: 884

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 11067419
• NCBI GeneID: 59326
• NCBI Accession #: NP_067722.1
• NCBI GenBank Nucleotide #: NM_021690.1
• Molecular Weight: 100,257 Da
• NCBI Official Full Name: rap guanine nucleotide exchange factor 3
• NCBI Official Synonym Full Names: Rap guanine nucleotide exchange factor 3
• NCBI Official Symbol: Rapgef3
• NCBI Official Synonym Symbols: Epac
• NCBI Protein Information: rap guanine nucleotide exchange factor 3
• UniProt Protein Name: Rap guanine nucleotide exchange factor 3
• Protein Family: Rap guanine nucleotide exchange factor
• UniProt Gene Name: Rapgef3
• UniProt Synonym Gene Names: Epac; Epac1; EPAC 1; cAMP-GEFI
• UniProt Entry Name: RPGF3_RAT

NCBI Description

binds cAMP and activates the Ras superfamily guanine nucleotide binding protein (Rap1A)in a PKA-independent manner [RGD, Feb 2006]

Uniprot Description

Epac1: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs, misc.; GEFs

Cellular Component: apical part of cell; basal plasma membrane; brush border membrane; cell soma; cortical actin cytoskeleton; filopodium; growth cone; lamellipodium; microvillus; nerve terminal; perinuclear region of cytoplasm; plasma membrane

Molecular Function: cAMP binding; guanyl-nucleotide exchange factor activity; protein binding; protein domain specific binding; Rap guanyl-nucleotide exchange factor activity

Biological Process: brain development; negative regulation of collagen biosynthetic process; positive regulation of angiogenesis; positive regulation of cell size; positive regulation of GTPase activity; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein amino acid phosphorylation; positive regulation of protein export from nucleus; positive regulation of smooth muscle cell migration; positive regulation of stress fiber formation; positive regulation of syncytium formation by plasma membrane fusion; positive regulation of transcription from RNA polymerase II promoter; Rap protein signal transduction; response to nicotine; spinal cord development