Rat FGFR1 oncogene partner 2 ELISA Kit | FGFR1OP2 elisa kit
Rat FGFR1 oncogene partner 2, FGFR1OP2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
FGFR1OP2: May be involved in wound healing pathway. A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity. Belongs to the SIKE family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Cellular Component: cytoplasm
Molecular Function: protein homodimerization activity
Biological Process: wound healing; response to wounding