Typical Testing Data/Standard Curve (for reference only)
Mouse Ferrochelatase, mitochondrial ELISA Kit | Fech elisa kit
Mouse Ferrochelatase, mitochondrial ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
FECH: Catalyzes the ferrous insertion into protoporphyrin IX. Defects in FECH are the cause of erythropoietic protoporphyria (EPP). Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. EPP is a form of porphyria marked by excessive protoporphyrin in erythrocytes, plasma, liver and feces, and by widely varying photosensitive skin changes ranging from a burning or pruritic sensation to erythema, edema and wheals. Belongs to the ferrochelatase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Lyase; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Mitochondrial; EC 4.99.1.1
Cellular Component: membrane; mitochondrial inner membrane; mitochondrion
Molecular Function: 2 iron, 2 sulfur cluster binding; ferrochelatase activity; heme binding; iron ion binding; iron-responsive element binding; iron-sulfur cluster binding; lyase activity; metal ion binding; tetrapyrrole binding
Biological Process: cholesterol metabolic process; detection of UV; erythrocyte differentiation; heme biosynthetic process; iron ion homeostasis; porphyrin biosynthetic process; protoporphyrinogen IX metabolic process; regulation of gene expression; regulation of hemoglobin biosynthetic process; response to light stimulus
Research Articles on Fech
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Product Notes
The Mouse Fech fech (Catalog #AAA2885842) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2885842 ELISA Kit recognizes Mouse Fech. It is sometimes possible for the material contained within the vial of "Ferrochelatase, mitochondrial, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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