Farnesyl-Diphosphate Farnesyltransferase 1 Recombinant Protein | FDFT1 recombinant protein
Recombinant Human Farnesyl-Diphosphate Farnesyltransferase 1
Gene Names
FDFT1; SS; SQS; DGPT; ERG9
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Farnesyl-Diphosphate Farnesyltransferase 1; Recombinant Human Farnesyl-Diphosphate Farnesyltransferase 1; FDFT1 Human; Farnesyl-Diphosphate Farnesyltransferase 1 Human Recombinant; Squalene Synthase; SQS; SS; FPP:FPP Farnesyltransferase; EC 2.5.1.21; DGPT; ERG9; Presqualene-Di-Diphosphate Synthase; Squalene Synthetase; Farnesyl-Diphosphate; Farnesyltransferase; FDFT1; FDFT1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
FDFT1 protein solution (0.25 mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMEFVKCL GHPEEFYNLV RFRIGGKRKV MPKMDQDSLS SSLKTCYKYLNQTSRSFAAV IQALDGEMRN AVCIFYLVLR ALDTLEDDMT ISVEKKVPLL HNFHSFLYQP DWRFMESKEKDRQVLEDFPT ISLEFRNLAE KYQTVIADIC RRMGIGMAEFLDKHVTSEQE WDKYCHYVAGLVGIGLSRLF SASEFEDPLV GEDTERANSM GLFLQKTNII RDYLEDQQGG REFWPQEVWS RYVKKLGDFA KPENIDLAVQCLNELITNAL HHIPDVITYL SRLRNQ
Sequence Length
417
Related Product Information for FDFT1 recombinant protein
Introduction: Farnesyl-Diphosphate Farnesyltransferase 1, also known as FDFT1 is a membrane-associated enzyme sited at a branch point in the mevalonate pathway. FDFT1
Description: FDFT1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 306 amino acids (1-283 a.a) and having a molecular mass of 35.4 kDa. FDFT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Description: FDFT1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 306 amino acids (1-283 a.a) and having a molecular mass of 35.4 kDa. FDFT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for FDFT1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,060 Da
NCBI Official Full Name
squalene synthase isoform 1
NCBI Official Synonym Full Names
farnesyl-diphosphate farnesyltransferase 1
NCBI Official Symbol
FDFT1
NCBI Official Synonym Symbols
SS; SQS; DGPT; ERG9
NCBI Protein Information
squalene synthase
UniProt Protein Name
Squalene synthase
UniProt Gene Name
FDFT1
UniProt Synonym Gene Names
SQS; SS
UniProt Entry Name
FDFT_HUMAN
Uniprot Description
FDFT1: a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]
Protein type: EC 2.5.1.21; Endoplasmic reticulum; Lipid Metabolism - steroid biosynthesis; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase; Transferase
Chromosomal Location of Human Ortholog: 8p23.1-p22
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane
Molecular Function: farnesyl-diphosphate farnesyltransferase activity
Biological Process: cholesterol biosynthetic process; farnesyl diphosphate metabolic process; steroid biosynthetic process
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Product Notes
The FDFT1 fdft1 (Catalog #AAA140735) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMEF VKCL GHPEEFYNLV RFRIGGKRKV MPKMDQDSLS SSLKTCYKYL NQTSRSFAAV IQALDGEMRN AVCIFYLVLR ALDTLEDDMT ISVEKKVPLL HNFHSFLYQP DWRFMESKEK DRQVLEDFPT ISLEFRNLAE KYQTVIADIC RRMGIGMAEF LDKHVTSEQE WDKYCHYVAG LVGIGLSRLF SASEFEDPLV GEDTERANSM GLFLQKTNII RDYLEDQQGG REFWPQEVWS RYVKKLGDFA KPENIDLAVQ CLNELITNAL HHIPDVITYL SRLRNQ. It is sometimes possible for the material contained within the vial of "Farnesyl-Diphosphate Farnesyltransferase 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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