SDS-PAGE
Squalene synthase (FDFT1) Recombinant Protein | FDFT1 recombinant protein
Recombinant Human Squalene synthase (FDFT1)
SDS-PAGE
SDS-PAGE
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]
Uniprot Description
FDFT1: a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]
Protein type: EC 2.5.1.21; Membrane protein, integral; Membrane protein, multi-pass; Transferase; Lipid Metabolism - steroid biosynthesis; Oxidoreductase; Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 8p23.1-p22
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane
Molecular Function: farnesyl-diphosphate farnesyltransferase activity; oxidoreductase activity
Biological Process: cellular lipid metabolic process; cholesterol biosynthetic process; farnesyl diphosphate metabolic process; isoprenoid biosynthetic process; steroid biosynthetic process
Research Articles on FDFT1
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Product Notes
The FDFT1 fdft1 (Catalog #AAA951511) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-417aa; Partial. The amino acid sequence is listed below: EFVKCLGHPE EFYNLVRFRI GGKRKVMPKM DQDSLSSSLK TCYKYLNQTS RSFAAVIQAL DGEMRNAVCI FYLVLRALDT LEDDMTISVE KKVPLLHNFH SFLYQPDWRF MESKEKDRQV LEDFPTISLE FRNLAEKYQT VIADICRRMG IGMAEFLDKH VTSEQEWDKY CHYVAGLVGI GLSRLFSASE FEDPLVGEDT ERANSMGLFL QKTNIIRDYL EDQQGGREFW PQEVWSRYVK KLGDFAKPEN IDLAVQCLNE LITNALHHIP DVITYLSRLR NQSVFNFCAI PQVMAIATLA ACYNNQQVFK GAVKIRKGQA VTLMMDATNM PAVKAIIYQY MEEIYHRIPD SDPSSSKTRQ IISTIRTQNL PNCQLISRSH YSPIYLSFVM LLAALSWQYL TTLSQVTEDY VQTGEH. It is sometimes possible for the material contained within the vial of "Squalene synthase (FDFT1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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