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CD23 recombinant protein

CD23 protein

Gene Names
Fcer2; CD23; Fcer2a
Applications
User optimized
Purity
> 96% pure
Synonyms
CD23; CD23 protein; FCeRII protein; Lymphocyte IgE receptor protein; Fc-epsilon-RII protein; BLAST-2 protein; CD 23 protein; CD-23 protein; CD 23; CD23 antigen protein; CD-23; CD23 recombinant protein
Ordering
For Research Use Only!
Host
Human
Purity/Purification
> 96% pure
Form/Format
Supplied as a lyophilized powder.
Sequence
Region of CD23 protein corresponding to amino acids MELQVSSGFV CNTCPEKWIN FQRKCYYFGK GTKQWVHARY ACDDMEGQLV SIHSPEEQDF LTKHASHTGS WIGLRNLDLK GEFIWVDGSH VDYSNWAPGE PTSRSQGEDC VMMRGSGRWN DAFCDRKLGA WVCDRLATCT PPASEGSAES MGPDSRPDPD GRLPTPSAPL HS.
Sequence Length
309
Applicable Applications for CD23 recombinant protein
User optimized
Protein Type
Recombinant
Biological Significance
CD23, the low affinity receptor for IgE, belongs to the C-type lectin structural family and plays a role in the regulation of IgE synthesis and IgE mediated activities. It is found both as a transmembrane receptor protein and in a soluble form, which is generated by proteolytic cleavage of membrane bound CD23. The predominant soluble form of CD23 (sCD23) consists of 172 amino acids corresponding to the extracellular domain of the full length precursor. sCD23, in addition to binding IgE, also exerts a number of IgE independent activities, such as promoting the activation and differentiation of B-cells and stimulating the release of pro-inflammatory cytokines from monocytes.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for CD23 recombinant protein
Purified recombinant Human CD23 protein
Product Categories/Family for CD23 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
19.2 kDa
NCBI Official Full Name
CD23
NCBI Official Synonym Full Names
Fc fragment of IgE, low affinity II, receptor for (CD23)
NCBI Official Symbol
Fcer2
NCBI Official Synonym Symbols
CD23; Fcer2a
NCBI Protein Information
low affinity immunoglobulin epsilon Fc receptor
UniProt Protein Name
CD23 protein
UniProt Gene Name
Fcer2
UniProt Entry Name
Q63097_RAT

NCBI Description

cell surface receptor; binds innumoglobulin (Ig)E and IgA antibodies [RGD, Feb 2006]

Research Articles on CD23

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Product Notes

The CD23 fcer2 (Catalog #AAA539501) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD23 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the CD23 fcer2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of CD23 protein correspond ing to amino acids MELQVSSGFV CNTCPEKWIN FQRKCYYFGK GTKQWVHARY ACDDMEGQLV SIHSPEEQDF LTKHASHTGS WIGLRNLDLK GEFIWVDGSH VDYSNWAPGE PTSRSQGEDC VMMRGSGRWN DAFCDRKLGA WVCDRLATCT PPASEGSAES MGPDSRPDPD GRLPTPSAPL HS. It is sometimes possible for the material contained within the vial of "CD23, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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