Human FAT tumor suppressor homolog 2 (Drosophila) ELISA Kit | FAT2 elisa kit

Human Protocadherin Fat 2, FAT2 ELISA Kit

Cat. Num. AAA9342143

• Gene Names: FAT2; CDHF8; CDHR9; HFAT2; MEGF1
• Reactivity: Human
• Synonyms: FAT tumor suppressor homolog 2 (Drosophila); Human Protocadherin Fat 2; FAT2 ELISA Kit; Human Protocadherin Fat 2 (FAT2) ELISA kit; CDHF8; HFAT2; MEGF1; FAT tumor suppressor 2; cadherin family member 8; multiple epidermal growth factor-like domains 1; protocadherin FAT2; FAT2 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Assay Type: Quantitative Sandwich
• Detection Range: 31.2pg/ml-1000pg/ml.
• Sensitivity: 5.0pg/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for FAT2 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of FAT2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 13787217
• NCBI GeneID: 2196
• NCBI Accession #: NP_001438.1
• NCBI GenBank Nucleotide #: NM_001447.2
• UniProt Accession #: Q9NYQ8; O75091; Q9NSR7
• Molecular Weight: 479,317 Da
• NCBI Official Full Name: protocadherin Fat 2
• NCBI Official Synonym Full Names: FAT atypical cadherin 2
• NCBI Official Symbol: FAT2
• NCBI Official Synonym Symbols: CDHF8; CDHR9; HFAT2; MEGF1
• NCBI Protein Information: protocadherin Fat 2; protocadherin FAT2; cadherin family member 8; FAT tumor suppressor homolog 2; cadherin-related family member 9; multiple EGF-like domains protein 1; multiple epidermal growth factor-like domains 1; multiple epidermal growth factor-like domains protein 1
• UniProt Protein Name: Protocadherin Fat 2
• Protein Family: Protocadherin
• UniProt Gene Name: FAT2
• UniProt Synonym Gene Names: CDHF8; KIAA0811; MEGF1; hFat2; Multiple EGF-like domains protein 1
• UniProt Entry Name: FAT2_HUMAN

NCBI Description

This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008]

Uniprot Description

FAT2: Plays a role in the migration of epidermal cells. May modulate the extracellular space surronding parallel fibers of cerebellar during development.

Protein type: Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: 5q33.1

Cellular Component: cell-cell adherens junction; plasma membrane; integral to membrane; nucleus

Molecular Function: calcium ion binding

Biological Process: homophilic cell adhesion