Rat family with sequence similarity 38, member A ELISA Kit | FAM38A elisa kit
Rat Protein PIEZO1, FAM38A ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PIEZO1: Component of mechanosensitive channel required for the mechanosensitive currents. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling. Belongs to the PIEZO family.
Protein type: Membrane protein, multi-pass; Endoplasmic reticulum; Membrane protein, integral
Cellular Component: endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; endoplasmic reticulum; integral to membrane; plasma membrane
Molecular Function: mechanically-gated ion channel activity; cation channel activity
Biological Process: regulation of membrane potential; detection of mechanical stimulus; positive regulation of integrin activation; positive regulation of cell-cell adhesion mediated by integrin; cation transport