Fatty Acid Binding Protein, Ileal Recombinant Protein | FABP6 recombinant protein

Fatty Acid Binding Protein, Ileal (IL-FABP), Recombinant, Human

Cat. Num. AAA637912

• Gene Names: FABP6; ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB
• Applications: ELISA
• Purity: Highly Purified; Purified. 95% by SDS-PAGE.
• Synonyms: Fatty Acid Binding Protein; Ileal; Ileal (IL-FABP); Recombinant; Human; FABP6 recombinant protein

• Host: Human, Recombinant, E Coli
• Purity/Purification: Highly Purified; Purified. 95% by SDS-PAGE.
• Form/Format: Supplied as a liquid.

• Applicable Applications for FABP6 recombinant protein: ELISA (EL/EIA)
• Application Notes: Suitable for use in ELISA., , Recommended Dilution:, Optimal dilutions to be determined by the researcher.
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for FABP6 recombinant protein

Recombinant IL-FABP comprises a 128 amino acid fragment (1-128) corresponding to the human ileal FABP protein and is expressed in E. coli with an amino- terminal hexahistidine tag.

Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins (14-15kDa) that bind long chain fatty acids, their CoA derivatives, billiruben, organic anions and other small hydrophobic molecules. They are abundantly present in various cell types and due to their small size rapidly leak from damaged cells leading to a rise in serum levels.

Product Categories/Family for FABP6 recombinant protein

Molecular Biology; MB-Fatty Acid Binding Protein

NCBI and Uniprot Product Information

• NCBI GI #: 119581970
• NCBI GeneID: 2172
• UniProt Accession #: P51161; Q07DR7; Q8TBI3; Q9UGI7
• Molecular Weight: 14,371 Da
• NCBI Official Full Name: fatty acid binding protein 6, ileal (gastrotropin), isoform CRA_d
• NCBI Official Synonym Full Names: fatty acid binding protein 6, ileal
• NCBI Official Symbol: FABP6
• NCBI Official Synonym Symbols: ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB
• NCBI Protein Information: gastrotropin; GT; intestinal 15 kDa protein; ileal lipid-binding protein; illeal lipid-binding protein; ileal bile acid binding protein
• UniProt Protein Name: Gastrotropin
• Protein Family: Gastrotropin
• UniProt Gene Name: FABP6
• UniProt Synonym Gene Names: ILBP; ILLBP; GT; ILBP; I-15P; I-BABP
• UniProt Entry Name: FABP6_HUMAN

NCBI Description

This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

FABP6: Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. 2 isoforms of the human protein are produced by alternative promoter.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 5q33.3-q34

Cellular Component: cytoplasm; cytosol

Molecular Function: transporter activity; lipid binding

Biological Process: bile acid and bile salt transport; negative regulation of cell proliferation; bile acid metabolic process; lipid metabolic process; transmembrane transport