FABP3 recombinant protein

FABP3, 1-133aa, Human, His tag, E Coli

Cat. Num. AAA203298

• Gene Names: FABP3; MDGI; FABP11; H-FABP; M-FABP; O-FABP
• Applications: SDS-Page
• Purity: > 95% by SDS-PAGE
• Synonyms: FABP3; 1-133aa; Human; His tag; E Coli; Fatty acid binding protein 3 muscle and heart; H-FABP; M-FABP; MDGI; FABP11; cardiac fabp; Fatty acid binding protein 3; muscle and heart Muscle fatty acid binding protein; 422 protein; Cardiac Fatty Acid Binding Protein; FABP 3.FABP3; Fatty acid binding protein 3 muscle; Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor; Fatty acid binding protein 11; Fatty acid binding protein heart; H FABP; Heart type fatty acid binding protein; M FABP; Mammary derived growth inhibitor; Mylein protein P2 homolog; O FABP; P2 adopocyte protein.; FABP3 recombinant protein

• Host: E Coli
• Purity/Purification: > 95% by SDS-PAGE
• Form/Format: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol
• Concentration: 1 mg/ml (determined by Bradford assay) (varies by lot)
• Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMVD AFLGTWKLVD SKNFDDYMKS LGVGFATRQV ASMTKPTTII EKNGDILTLK THSTFKNTEI SFKLGVEFDE TTADDRKVKS IVTLDGGKLV HLQKWDGQET TLVRELIDGK LILTLTHGTA VCTRTYEKEA
• Sequence Length: 133

• Applicable Applications for FABP3 recombinant protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for FABP3 recombinant protein

FABP3 (Fatty acid binding protein 3) is also known as heart fatty acid binding protein and is a member of Fatty acid binding proteins (FABPs) which are a family of small, highly conserved, cytoplasmic proteins to bind long-chain fatty acids and other hydrophobic ligands. FABP3 is abundant in the myocardium and rapidly released from cardiomyocytes into the circulation after the onset of cell damage. Therefore, this protein has been proposed as an early biochemical marker of acute myocardial infarction and a sensitive marker for the detection and evaluation of myocardial damage in patients with heart failure. Recombinant FABP3 protein was expressed in E Coli and purified by using conventional chromatography techniques.

Product Categories/Family for FABP3 recombinant protein

Transportation

References

Troxler RF., et al. (2007). Hum Genet. 92 (6):563-6; Zanotti G., et al. (1992). J Biol Chem. 267 (26):18541-50;

NCBI and Uniprot Product Information

• NCBI GI #: 4758328
• NCBI GeneID: 2170
• NCBI Accession #: NP_004093
• NCBI GenBank Nucleotide #: NM_004102.4
• UniProt Accession #: P05413; Q5VV93; Q99957; B2RAB6
• Molecular Weight: 19.1 kDa (170aa), confirmed by MALDI-TOF.
• NCBI Official Full Name: fatty acid-binding protein, heart isoform 2
• NCBI Official Synonym Full Names: fatty acid binding protein 3
• NCBI Official Symbol: FABP3
• NCBI Official Synonym Symbols: MDGI; FABP11; H-FABP; M-FABP; O-FABP
• NCBI Protein Information: fatty acid-binding protein, heart
• UniProt Protein Name: Fatty acid-binding protein, heart
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP3
• UniProt Synonym Gene Names: FABP11; MDGI; H-FABP; MDGI; M-FABP

NCBI Description

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Uniprot Description

FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.