Fatty Acid Binding Protein | FABP protein
Fatty acid binding protein (FABP), human
Product is recommended to reconstitute with distilled water.
Blood sample from the tissue donor was tested and found negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis.
FABP is a newly introduced plasma marker of acute mydegree Cardial infarction (AMI). The plasma kinetics of FABP (15 kD) closely resemble those of myoglobin in that elevated plasma concentrations are found within 2 hours after AMI and return to normal generally within 18 to 24 hours. But the concentration of FABP in the skeletal muscle is 20 times lower than in cardiac tissue (for myoglobin the same content for cardiac and skeletal tissue), that makes FABP to be more cardiac specific than myoglobin. This makes FABP a useful bidegree Chemical marker for the early assessment or exclusion of AMI. FABP also appears to be a useful plasma marker for the estimation of mydegree Cardial infarct size.
Immunological identity confirmed by reaction with monoclonal antibody that is specific for the fatty acid binding protein.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
Uniprot Description
FABP7: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein type: Lipid-binding; Cell development/differentiation; Cell cycle regulation
Chromosomal Location of Human Ortholog: 6q22-q23
Cellular Component: cell projection; cell soma; cytoplasm; nucleus
Molecular Function: transporter activity; lipid binding
Biological Process: negative regulation of cell proliferation; nervous system development; epithelial cell proliferation; prepulse inhibition; neurogenesis; transport; cell proliferation in forebrain
Research Articles on FABP
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Product Notes
The FABP fabp7 (Catalog #AAA664062) is a Protein and is intended for research purposes only. The product is available for immediate purchase. FABP is suitable for use as a standard in immunoassay for early detection of acute mydegree Cardial infarction, immunogen for antisera production, mass FABP standard, FABP bidegree Chemical and immundegree Chemical studies, tracer for iodination. Researchers should empirically determine the suitability of the FABP fabp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Fatty Acid Binding Protein, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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