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Mouse Proteinase-activated receptor 1 ELISA Kit | F2r elisa kit

Mouse Proteinase-activated receptor 1 ELISA Kit

Gene Names
F2r; Cf2r; Par1; ThrR; AI482343
Reactivity
Mouse
Synonyms
Proteinase-activated receptor 1; Mouse Proteinase-activated receptor 1 ELISA Kit; PAR-1; Thrombin receptor; F2r; Cf2r; Par1; F2r elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Samples
Serum, plasma, tissue homogenates and other biological fluids.
Detection Range
0.312-20 ng/mL
Assay Time
3-5h
Sample Volume
100T
Detection Wavelength
450 nm
Preparation and Storage
Store at 4 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,790 Da
NCBI Official Full Name
proteinase-activated receptor 1
NCBI Official Synonym Full Names
coagulation factor II (thrombin) receptor
NCBI Official Symbol
F2r
NCBI Official Synonym Symbols
Cf2r; Par1; ThrR; AI482343
NCBI Protein Information
proteinase-activated receptor 1
UniProt Protein Name
Proteinase-activated receptor 1
UniProt Gene Name
F2r
UniProt Synonym Gene Names
Cf2r; Par1; PAR-1

Uniprot Description

PAR1: a G-protein coupled high-affinity receptor for activated thrombin or trypsin. Coupled to G proteins that stimulate phosphoinositide hydrolysis. Coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelet activation and in vascular development.

Protein type: Cell development/differentiation; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 13 D1|13 50.21 cM

Cellular Component: caveola; cell surface; early endosome; integral to plasma membrane; late endosome; neuromuscular junction; plasma membrane; postsynaptic membrane

Molecular Function: G-protein alpha-subunit binding; G-protein beta-subunit binding; G-protein coupled receptor activity; heterotrimeric G-protein binding; receptor binding; thrombin receptor activity

Biological Process: activation of MAPKK activity; caspase activation; connective tissue replacement during inflammatory response; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); establishment of synaptic specificity at neuromuscular junction; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); homeostasis of number of cells within a tissue; inflammatory response; negative regulation of cell proliferation; negative regulation of glomerular filtration; negative regulation of neuron apoptosis; platelet activation; positive regulation of blood coagulation; positive regulation of calcium ion transport; positive regulation of caspase activity; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of JAK-STAT cascade; positive regulation of MAPKKK cascade; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of Rho protein signal transduction; positive regulation of smooth muscle contraction; positive regulation of transcription, DNA-dependent; positive regulation of vasoconstriction; protein kinase C activation; regulation of blood coagulation; regulation of interleukin-1 beta production; regulation of sensory perception of pain; release of sequestered calcium ion into cytosol; response to lipopolysaccharide; response to wounding; STAT protein nuclear translocation; tyrosine phosphorylation of STAT protein

Research Articles on F2r

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Product Notes

The Mouse F2r f2r (Catalog #AAA9426145) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9426145 ELISA Kit recognizes Mouse F2r. It is sometimes possible for the material contained within the vial of "Proteinase-activated receptor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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