Exocyst Complex Component 3 Recombinant Protein | EXOC3 recombinant protein

Recombinant Exocyst Complex Component 3 (EXOC3)

Cat. Num. AAA2034649

• Gene Names: EXOC3; SEC6; Sec6p; SEC6L1
• Reactivity: Rat
• Applications: ELISA, Immunoprecipitation, SDS-Page, Western Blot
• Purity: > 90%
• Synonyms: Exocyst Complex Component 3; Recombinant Exocyst Complex Component 3 (EXOC3); Exocyst complex component Sec6; EXOC3 recombinant protein

• Host: E Coli; Source: Prokaryotic expression
• Reactivity: Rat
• Purity/Purification: > 90%
• Form/Format: Freeze-dried powder
• Sequence Length: 745

• Applicable Applications for EXOC3 recombinant protein: SDS-PAGE; Western Blot (WB); ELISA (EIA); Immunoprecipitation (IP)
• Usage: Reconstitute in PBS or others.
• Endotoxin Level: < 1.0EU per 1ug (determined by the LAL method)
• Buffer Formulation: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Fragment: Gln447~Lys755
• Tag: Two N-terminal Tags, His-tag and T7-tag
• Residues & Tags: Gln447~Lys755 with N-terminal His Tag
• Subcellular Location: Secreted
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 31083351
• NCBI GeneID: 11336
• NCBI Accession #: NP_009208.2
• NCBI GenBank Nucleotide #: NM_007277.4
• Molecular Weight: Predicted: 39.1kDa
• NCBI Official Full Name: exocyst complex component 3
• NCBI Official Synonym Full Names: exocyst complex component 3
• NCBI Official Symbol: EXOC3
• NCBI Official Synonym Symbols: SEC6; Sec6p; SEC6L1
• NCBI Protein Information: exocyst complex component 3
• UniProt Protein Name: Exocyst complex component 3
• Protein Family: Exocyst complex component
• UniProt Gene Name: EXOC3
• UniProt Synonym Gene Names: SEC6; SEC6L1
• UniProt Entry Name: EXOC3_HUMAN

NCBI Description

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]

Uniprot Description

SEC6L1: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC6 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 5p15.33

Cellular Component: cytosol; exocyst; secretory granule membrane

Molecular Function: protein binding; SNARE binding

Biological Process: exocyst localization; exocytosis