Exonuclease 3'-5' domain-containing protein 1 (exd1) Recombinant Protein | exd1 recombinant protein
Recombinant Danio rerio Exonuclease 3'-5' domain-containing protein 1 (exd1)
Gene Names
exd1; zgc:154068
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Exonuclease 3'-5' domain-containing protein 1 (exd1); Recombinant Danio rerio Exonuclease 3'-5' domain-containing protein 1 (exd1); exd1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-378, Full length protein
Sequence
MNNRLNTTSSSEESRFLEEMKRKRVNITLSDTEISGVIQKITQKKTLILEDVSEVRSGRRFPGAKLIFGKEIVKVEFPLSAGQASVFSNEKHKSEFQTFKKKMTLDGEEDGVSYVLIDELHEKFGPAVMHIQEQDVIGIGADVYGQSGQERLCWLQVATKKVVYLFDILLLGGPAFKNGLSMILENTHILKVLHDCRCITRCLRTEFRVQLTNVFDTQVAELLLFFNESGGFLPDRPASLPELLQLHLRLTTAEIQPLCSKQQQSRECVQLWYVRPCPPDLLSLMCSSVQHLLSLRLLLLDALLADYTVLVDSFMSSSHCPPLHFQQDECAVPPELQELMCVRQQRMDWASQCYSQTDSGLLQRSSFKASPHTPADAQ
Sequence Length
378
Species
Zebrafish
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,794 Da
NCBI Official Full Name
piRNA biogenesis protein EXD1
NCBI Official Synonym Full Names
exonuclease 3'-5' domain containing 1
NCBI Official Symbol
exd1
NCBI Official Synonym Symbols
zgc:154068
NCBI Protein Information
piRNA biogenesis protein EXD1
UniProt Protein Name
piRNA biogenesis protein EXD1
Protein Family
UniProt Gene Name
exd1
UniProt Synonym Gene Names
exdl1
Uniprot Description
RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity. The PET complex is required during the secondary piRNAs metabolic process for the piwil2 slicing-triggered loading of piwil4 piRNAs. In the PET complex, exd1 probably acts as an RNA adapter. Exd1 is an inactive exonuclease.
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Product Notes
The exd1 exd1 (Catalog #AAA1391824) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-378, Full length protein. The amino acid sequence is listed below: MNNRLNTTSS SEESRFLEEM KRKRVNITLS DTEISGVIQK ITQKKTLILE DVSEVRSGRR FPGAKLIFGK EIVKVEFPLS AGQASVFSNE KHKSEFQTFK KKMTLDGEED GVSYVLIDEL HEKFGPAVMH IQEQDVIGIG ADVYGQSGQE RLCWLQVATK KVVYLFDILL LGGPAFKNGL SMILENTHIL KVLHDCRCIT RCLRTEFRVQ LTNVFDTQVA ELLLFFNESG GFLPDRPASL PELLQLHLRL TTAEIQPLCS KQQQSRECVQ LWYVRPCPPD LLSLMCSSVQ HLLSLRLLLL DALLADYTVL VDSFMSSSHC PPLHFQQDEC AVPPELQELM CVRQQRMDWA SQCYSQTDSG LLQRSSFKAS PHTPADAQ. It is sometimes possible for the material contained within the vial of "Exonuclease 3'-5' domain-containing protein 1 (exd1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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