Human ets variant 7 ELISA Kit | ETV7 elisa kit
Human Transcription factor ETV7, ETV7 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).[provided by RefSeq, May 2011]
Uniprot Description
ETV7: Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity. Belongs to the ETS family. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 6p21
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; organ morphogenesis; negative regulation of transcription from RNA polymerase II promoter; cell differentiation
Research Articles on ETV7
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Product Notes
The Human ETV7 etv7 (Catalog #AAA9323982) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323982 ELISA Kit recognizes Human ETV7. It is sometimes possible for the material contained within the vial of "ets variant 7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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