Mouse ets variant 1 ELISA Kit | ETV1 elisa kit
Mouse ETS transloCation variant 1, ETV1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ETV1: Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'. Defects in ETV1 are a cause of Ewing sarcoma (ES). A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. A chromosomal aberration involving ETV1 is found in patients with Erwing sarcoma. Translocation t(7;22)(p22;q12) with EWSR1. Belongs to the ETS family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Oncoprotein; Transcription factor
Cellular Component: nucleus
Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; axon guidance; muscle development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; mechanosensory behavior; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
Research Articles on ETV1
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Product Notes
The Mouse ETV1 etv1 (Catalog #AAA9331143) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331143 ELISA Kit recognizes Mouse ETV1. It is sometimes possible for the material contained within the vial of "ets variant 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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