Rat v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) ELISA Kit | ETS1 elisa kit

Rat Protein C-ets-1, ETS1 ELISA Kit

Cat. Num. AAA9334021

• Gene Names: Ets1; Tpl1; Ets-1; Etsoncb
• Reactivity: Rat
• Synonyms: v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Rat Protein C-ets-1; ETS1 ELISA Kit; Rat Protein C-ets-1 (ETS1) ELISA kit; ETS-1; EWSR2; FLJ10768; Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; ets protein; v-ets avian erythroblastosis virus E2 oncogene homolog 1; v-ets avian erythroblastosis virus E26 oncoge; ETS1 elisa kit

• Reactivity: Rat

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 6978819
• NCBI GeneID: 24356
• NCBI Accession #: NP_036687.1
• NCBI GenBank Nucleotide #: NM_012555.2
• UniProt Accession #: P41156; Q3T1H1
• Molecular Weight: 50,423 Da
• NCBI Official Full Name: protein C-ets-1
• NCBI Official Synonym Full Names: v-ets avian erythroblastosis virus E26 oncogene homolog 1
• NCBI Official Symbol: Ets1
• NCBI Official Synonym Symbols: Tpl1; Ets-1; Etsoncb
• NCBI Protein Information: protein C-ets-1; p54; v-ets erythroblastosis virus E26 oncogene homolog 1; Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1)
• UniProt Protein Name: Protein C-ets-1
• Protein Family: Protein
• UniProt Gene Name: Ets1
• UniProt Synonym Gene Names: Ets-1
• UniProt Entry Name: ETS1_RAT

NCBI Description

activates transcription of cyclin-dependent kinase inhibitor p21WAF1/Cip1; plays a role in inhibition of apoptosis [RGD, Feb 2006]

Uniprot Description

Ets-1: a proto-oncogenic transcription factor homologous to the v-ets erythroblastosis virus oncogene. The DNA binding activity of Ets1 is controlled by kinases and transcription factors. It contributes to the regulation of cellular differentiation in hematopoietic cells. Ets1 promotes invasive behavior in endothelial cells, vascular smooth muscle cells and epithelial cancer cells. Regulates the expression of MMP1, MMP3, MMP9 and uPA as well as of VEGF and VEGFR gene expression. Two alternatively spliced isoforms have been described.

Protein type: Motility/polarity/chemotaxis; Oncoprotein; Transcription factor; DNA-binding

Cellular Component: nucleoplasm; transcription factor complex; intercellular bridge; cytoplasm; nucleus

Molecular Function: histone acetyltransferase binding; protein binding; DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; hypothalamus development; positive regulation of transcription, DNA-dependent; cell motility involved in cell locomotion; PML body organization and biogenesis; female pregnancy; response to estradiol stimulus; negative regulation of cell cycle; regulation of apoptosis; response to antibiotic; positive regulation of cell proliferation; response to wounding; cell differentiation; immune system process; positive regulation of erythrocyte differentiation; positive regulation of cell motility; angiogenesis involved in wound healing; regulation of angiogenesis; regulation of transcription from RNA polymerase II promoter; positive regulation of angiogenesis; pituitary gland development; response to mechanical stimulus; response to hypoxia; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell migration