ERO1-like protein alpha (ERO1L) Recombinant Protein | ERO1L recombinant protein
Recombinant Human ERO1-like protein alpha (ERO1L)
Gene Names
ERO1A; ERO1L; ERO1-L; ERO1LA; Ero1alpha; ERO1-alpha; ERO1-L-alpha
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
ERO1-like protein alpha (ERO1L); Recombinant Human ERO1-like protein alpha (ERO1L); ERO1L recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
24-468, Full length protein
Sequence
EEQPPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKYSEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDENSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH
Sequence Length
445
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,393 Da
NCBI Official Full Name
ERO1-like protein alpha
NCBI Official Synonym Full Names
endoplasmic reticulum oxidoreductase 1 alpha
NCBI Official Symbol
ERO1A
NCBI Official Synonym Symbols
ERO1L; ERO1-L; ERO1LA; Ero1alpha; ERO1-alpha; ERO1-L-alpha
NCBI Protein Information
ERO1-like protein alpha
UniProt Protein Name
ERO1-like protein alpha
Protein Family
UniProt Gene Name
ERO1A
UniProt Synonym Gene Names
ERO1-L; ERO1-L-alpha
Uniprot Description
Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.
Research Articles on ERO1L
Similar Products
Product Notes
The ERO1L ero1a (Catalog #AAA1443075) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 24-468, Full length protein. The amino acid sequence is listed below: EEQPPETAAQ RCFCQVSGYL DDCTCDVETI DRFNNYRLFP RLQKLLESDY FRYYKVNLKR PCPFWNDISQ CGRRDCAVKP CQSDEVPDGI KSASYKYSEE ANNLIEECEQ AERLGAVDES LSEETQKAVL QWTKHDDSSD NFCEADDIQS PEAEYVDLLL NPERYTGYKG PDAWKIWNVI YEENCFKPQT IKRPLNPLAS GQGTSEENTF YSWLEGLCVE KRAFYRLISG LHASINVHLS ARYLLQETWL EKKWGHNITE FQQRFDGILT EGEGPRRLKN LYFLYLIELR ALSKVLPFFE RPDFQLFTGN KIQDEENKML LLEILHEIKS FPLHFDENSF FAGDKKEAHK LKEDFRLHFR NISRIMDCVG CFKCRLWGKL QTQGLGTALK ILFSEKLIAN MPESGPSYEF HLTRQEIVSL FNAFGRISTS VKELENFRNL LQNIH. It is sometimes possible for the material contained within the vial of "ERO1-like protein alpha (ERO1L), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
