C-5 sterol desaturase (ERG3) Recombinant Protein | ERG3 recombinant protein
Recombinant Saccharomyces cerevisiae C-5 sterol desaturase (ERG3)
NCBI and Uniprot Product Information
Uniprot Description
Function: Catalyzes the introduction of a C-5 double bond in the B ring of ergosterol. May contribute to the regulation of ergosterol biosynthesis.
Cofactor: Iron
By similarity.
Pathway: Steroid metabolism; ergosterol biosynthesis; ergosterol from zymosterol: step 3/5.
Subunit structure: Interacts with ERG28. Ref.9
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Probable.
Domain: The histidine box domains may contain the active site and/or be involved in metal ion binding.
Miscellaneous: Present with 36200 molecules/cell in log phase SD medium.
Sequence similarities: Belongs to the sterol desaturase family.
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Product Notes
The ERG3 erg3 (Catalog #AAA1117318) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-365. The amino acid sequence is listed below: MDLVLEVADH YVLDDLYAKV LPASLAANIP VKWQKLLGLN SGFSNSTILQ ETLNSKNAVK ECRRFYGQVP FLFDMSTTSF ASLLPRSSIL REFLSLWVIV TIFGLLLYLF TASLSYVFVF DKSIFNHPRY LKNQMAMEIK LAVSAIPWMS MLTVPWFVME LNGHSKLYMK IDYENHGVRK LIIEYFTFIF FTDCGVYLAH RWLHWPRVYR ALHKPHHKWL VCTPFASHSF HPVDGFLQSI SYHIYPLILP LHKVSYLILF TFVNFWTVMI HDGQYLSNNP AVNGTACHTV HHLYFNYNYG QFTTLWDRLG GSYRRPDDSL FDPKLRDAKE TWDAQVKEVE HFIKEVEGDD NDRIYENDPN TKKNN. It is sometimes possible for the material contained within the vial of "C-5 sterol desaturase (ERG3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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