Ephrin type-A receptor 4a (epha4a) Recombinant Protein | epha4a recombinant protein
Recombinant Danio rerio Ephrin type-A receptor 4a (epha4a)
NCBI and Uniprot Product Information
Uniprot Description
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including efna1 and efnb3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections ().
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Product Notes
The epha4a epha4a (Catalog #AAA1117156) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-292, Full length protein. The amino acid sequence is listed below: IGIGEFGEVC SGRLKMPGKR EICVAIKTLK AGYTDKQRRD FLSEASIMGQ FDHPNIIRLE GVVTKCKPVM IITEYMENGS LDAFLRKNDG RFTVIQLVGI LRGIASGMKY LSDMSYVHRD LAARNILVNS NLVCKVSDFG MSRVLEEDPD AAYTTREITG TYQSQGGKIP IRWTAPEAIT YRKFTSASDV WSYGIVMWEV MSYGERPYWD MSNQDVIKAI EEGYRLPPPM DCPVSLHQLM LDCWQKERAE RPKFSQIVNM LDKLIRNPNS LKRTGGEIAR PNTTLLEPSS PE. It is sometimes possible for the material contained within the vial of "Ephrin type-A receptor 4a (epha4a), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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