Envelope glycoprotein (env) Recombinant Protein | env recombinant protein
Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein (env), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Envelope glycoprotein (env); Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein (env); partial; env recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
85-378
Sequence
AYIPDP PMIQSLGWDR EIVPVYVNDT SLLGGKSDIH ISPQQANISF YGLTTQYPMC FSYQSQHPHC IQVSADISYP RVTISGIDEK TGKKSYGNGT GPLDIPFCDK HLSIGIGIDT PWTLCRARVA SVYNINNANA TFLWDWAPGG TPDFPEYRGQ HPPIFSVNTA PIYQTELWKL LAAFGHGNSL YLQPNISGTK YGDVGVTGFL YPRACVPYPF MLIQGHMEIT LSLNIYHLNC SNCILTNCIR GVAKGEQVII VKQPAFVMLP VEIAEAWYDE TALELLQRIN TALSRPKR
Sequence Length
294
Species
Sheep pulmonary adenomatosis virus (Jaagsiekte sheep retrovirus) (JSRV)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,343 Da
NCBI Official Full Name
envelope protein
NCBI Official Symbol
env
NCBI Protein Information
envelope protein
UniProt Protein Name
Envelope glycoprotein
Protein Family
UniProt Gene Name
env
UniProt Synonym Gene Names
SU; gp52; TM; gp36
Uniprot Description
The envelope proteins induce cell transformation leading to ovine pulmonary adenocarcinoma (OPA), a contagious lung cancer of sheep and goat. They bind to the HYAL2 receptor for cell entry. Env proteins probably do not act as oncogenes by themselves, but may rather liberate an oncogenic factor that would normally be negatively regulated. One mechanism of transformation seems to involve activation of the phosphoinositide-3-OH kinase (PI3K)/Akt pathway but does not involve the virus receptor HYAL2, and the other seems to involve Env binding to HYAL2, HYAL2 degradation, and activation of the MST1R receptor tyrosine kinase, which is normally suppressed by HYAL2.
Research Articles on env
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Product Notes
The env env (Catalog #AAA1018265) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 85-378. The amino acid sequence is listed below: AYIPDP PMIQSLGWDR EIVPVYVNDT SLLGGKSDIH ISPQQANISF YGLTTQYPMC FSYQSQHPHC IQVSADISYP RVTISGIDEK TGKKSYGNGT GPLDIPFCDK HLSIGIGIDT PWTLCRARVA SVYNINNANA TFLWDWAPGG TPDFPEYRGQ HPPIFSVNTA PIYQTELWKL LAAFGHGNSL YLQPNISGTK YGDVGVTGFL YPRACVPYPF MLIQGHMEIT LSLNIYHLNC SNCILTNCIR GVAKGEQVII VKQPAFVMLP VEIAEAWYDE TALELLQRIN TALSRPKR. It is sometimes possible for the material contained within the vial of "Envelope glycoprotein (env), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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