Human eukaryotic translation initiation factor 5A ELISA Kit | EIF5A elisa kit
Human Eukaryotic translation initiation factor 5A-1, EIF5A ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
EIF5A: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF- alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts. Belongs to the eIF-5A family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation; Translation initiation
Chromosomal Location of Human Ortholog: 17p13-p12
Cellular Component: endoplasmic reticulum membrane; membrane; cytoplasm; nuclear pore; nucleus; cytosol; annulate lamellae
Molecular Function: protein binding; RNA binding; ribosome binding; protein N-terminus binding; translation elongation factor activity; U6 snRNA binding
Biological Process: mRNA export from nucleus; cellular protein metabolic process; translational frameshifting; apoptosis; positive regulation of cell proliferation; positive regulation of translational elongation; hypusine biosynthetic process from peptidyl-lysine; nucleocytoplasmic transport; protein export from nucleus; post-translational protein modification; positive regulation of translational termination
Research Articles on EIF5A
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Product Notes
The Human EIF5A eif5a (Catalog #AAA9340205) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9340205 ELISA Kit recognizes Human EIF5A. It is sometimes possible for the material contained within the vial of "eukaryotic translation initiation factor 5A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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