Human eukaryotic translation initiation factor 4A, isoform 2 ELISA Kit | EIF4A2 elisa kit
Human Eukaryotic initiation factor 4A-II, EIF4A2/DDX2B/EIF4F ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
EIF4A2: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. Belongs to the DEAD box helicase family. eIF4A subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.4.13; Translation initiation; Helicase; Translation; RNA-binding
Chromosomal Location of Human Ortholog: 3q28
Cellular Component: perinuclear region of cytoplasm; eukaryotic translation initiation factor 4F complex; cytosol
Molecular Function: protein binding; translation initiation factor activity; ATPase activity; helicase activity; ATP binding
Biological Process: poly(A) tail shortening; cellular protein metabolic process; viral reproduction; translation; cytokine and chemokine mediated signaling pathway; translational initiation; gene expression; regulation of translational initiation; mRNA catabolic process, deadenylation-dependent decay
Research Articles on EIF4A2
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Product Notes
The Human EIF4A2 eif4a2 (Catalog #AAA9310742) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9310742 ELISA Kit recognizes Human EIF4A2. It is sometimes possible for the material contained within the vial of "eukaryotic translation initiation factor 4A, isoform 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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