Eukaryotic translation initiation factor 3 subunit J (Eif3j) Recombinant Protein | Eif3j recombinant protein
Recombinant Rat Eukaryotic translation initiation factor 3 subunit J (Eif3j)
NCBI and Uniprot Product Information
Uniprot Description
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
Research Articles on Eif3j
Similar Products
Product Notes
The Eif3j eif3j (Catalog #AAA959151) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-259, Full length protein. The amino acid sequence is listed below: MAAAAAAAAG DSDSWDADTF SMEDPVRKVA GGGTAGGDRW EGEDEDEDVK DNWDDDDDEN KEEAEVKPEV KISEKKKIAE KIKEKERQQK KRQEEIKKRL EEPEESKVLT PEEQLADKLR LKKLQEESDL ELAKETFGVN NTVYGIDAMN PSSRDDFTEF GKLLKDKITQ YEKSLYYASF LEALVRDVCI SLEIDDLKKI TNSLTVLCSE KQKQEKQSKA KKKKKGVVPG GGLKATMKDD LADYGGYDGG YVQDYEDFM. It is sometimes possible for the material contained within the vial of "Eukaryotic translation initiation factor 3 subunit J (Eif3j), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
