Human eukaryotic translation initiation factor 2C, 4 ELISA Kit | EIF2C4 elisa kit
Human Protein argonaute-4, EIF2C4 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic containing PAZ and PIWI domains, and it may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a cluster of closely related family members including argonaute 3, and eukaryotic translation initiation factor 2C, 1. [provided by RefSeq, Jul 2008]
Uniprot Description
AGO4: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). Interacts with EIF4B, IMP8, PRMT5, TNRC6A and TNRC6B. Belongs to the argonaute family. Ago subfamily.
Protein type: Translation initiation; Translation
Chromosomal Location of Human Ortholog: 1p34
Cellular Component: membrane; cytoplasm; cytosol
Molecular Function: protein binding; miRNA binding
Biological Process: epidermal growth factor receptor signaling pathway; Notch signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; miRNA-mediated gene silencing, mRNA cleavage; mRNA catabolic process; innate immune response; miRNA-mediated gene silencing, negative regulation of translation; gene expression; posttranscriptional gene silencing
Research Articles on EIF2C4
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Product Notes
The Human EIF2C4 ago4 (Catalog #AAA9327938) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327938 ELISA Kit recognizes Human EIF2C4. It is sometimes possible for the material contained within the vial of "eukaryotic translation initiation factor 2C, 4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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