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Ephrin B2 Recombinant Protein | EFNB2 recombinant protein

Recombinant Ephrin B2 (EFNB2)

Gene Names
efnb2a; efnb2; id:ibd5072
Applications
SDS-Page, Western Blot
Purity
>95%
Synonyms
Ephrin B2; Recombinant Ephrin B2 (EFNB2); EPLG5; HTKL; Htk-L; LERK5; HTK Ligand; Ligand Of Eph-Related Kinase 5; Eph-Related Receptor Tyrosine Kinase Ligand 5; EFNB2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
>95%
Form/Format
Freeze-dried powder
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Sequence Positions
Leu25~Asn193
Sequence Length
332
Applicable Applications for EFNB2 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Source
Prokaryotic expression
Species
Zebrafish
Tag
N-terminal His Tag
Subcellular Location
Membrane, Single-pass Type I Membrane Protein
Isoelectric Point
5.9
Reconstitution
Reconstitute in PBS or others.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for EFNB2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted Molecular Mass: 22.7kDa
Accurate Molecular Mass: 23kDa
NCBI Official Full Name
ephrin-B2a
NCBI Official Synonym Full Names
ephrin-B2a
NCBI Official Symbol
efnb2a
NCBI Official Synonym Symbols
efnb2; id:ibd5072
NCBI Protein Information
ephrin-B2a
UniProt Protein Name
Ephrin-B2a
Protein Family
UniProt Gene Name
efnb2a
UniProt Synonym Gene Names
efnb2
UniProt Entry Name
EFNB2_DANRE

Uniprot Description

Function: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration

By similarity.

Subunit structure: Binds to the receptor tyrosine kinase ephb4.

Subcellular location: Membrane; Single-pass type I membrane protein.

Post-translational modification: Inducible phosphorylation of tyrosine residues in the cytoplasmic domain

By similarity.

Sequence similarities: Belongs to the ephrin family.Contains 1 ephrin RBD (ephrin receptor-binding) domain.

Research Articles on EFNB2

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Product Notes

The EFNB2 efnb2a (Catalog #AAA2123219) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Leu25~Asn193. AAA Biotech's Ephrin B2 can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the EFNB2 efnb2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ephrin B2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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