Hamster Eosinophil Cationic Protein ELISA Kit | ECP elisa kit

Hamster Eosinophil Cationic Protein ELISA Kit

Cat. Num. AAA28050

• Gene Names: RNASE3; ECP; RNS3
• Reactivity: Hamster
• Synonyms: Eosinophil Cationic Protein; Hamster Eosinophil Cationic Protein ELISA Kit; ECP elisa kit

• Reactivity: Hamster
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples.
• Assay Type: Sandwich (Quantitative)
• Detection Range: 1.56 ng/ml - 50 ng/ml.
• Sensitivity: 0.1 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for ECP elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of ECP (hereafter termed "analyte") in undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 45243507
• NCBI GeneID: 6037
• NCBI Accession #: NP_002926.2
• NCBI GenBank Nucleotide #: NM_002935.2
• UniProt Accession #: P12724; Q4VBC1; Q8WTP7; Q8WZ62; Q9GZN9
• Molecular Weight: 18,385 Da
• NCBI Official Full Name: eosinophil cationic protein
• NCBI Official Synonym Full Names: ribonuclease, RNase A family, 3
• NCBI Official Symbol: RNASE3
• NCBI Official Synonym Symbols: ECP; RNS3
• NCBI Protein Information: eosinophil cationic protein; RNase 3; ribonuclease 3; cytotoxic ribonuclease
• UniProt Protein Name: Eosinophil cationic protein
• Protein Family: Eosinophil cationic protein
• UniProt Gene Name: RNASE3
• UniProt Synonym Gene Names: ECP; RNS3; ECP; RNase 3
• UniProt Entry Name: ECP_HUMAN

NCBI Description

The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014]

Uniprot Description

RNASE3: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. Belongs to the pancreatic ribonuclease family.

Protein type: Ribonuclease; Secreted, signal peptide; Secreted; EC 3.1.27.-

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: extracellular space; extracellular region

Molecular Function: nucleic acid binding; endonuclease activity; ribonuclease activity

Biological Process: defense response to Gram-positive bacterium; innate immune response in mucosa; RNA catabolic process; antibacterial humoral response