Human Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase ELISA Kit | ECH1 elisa kit
Human Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. [provided by RefSeq, Jul 2008]
Uniprot Description
ECH1: Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA. Belongs to the enoyl-CoA hydratase/isomerase family.
Protein type: Mitochondrial; EC 5.3.3.-; Amino Acid Metabolism - tyrosine; Isomerase
Chromosomal Location of Human Ortholog: 19q13.1
Cellular Component: membrane; mitochondrion; peroxisome
Molecular Function: isomerase activity; protein binding; receptor binding
Biological Process: fatty acid beta-oxidation
Research Articles on ECH1
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Product Notes
The Human ECH1 ech1 (Catalog #AAA2884373) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2884373 ELISA Kit recognizes Human ECH1. It is sometimes possible for the material contained within the vial of "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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