Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

ESX-1 secretion system protein EccCa1 (eccCa1) Recombinant Protein | eccCa1 recombinant protein

Recombinant ESX-1 secretion system protein EccCa1 (eccCa1)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
ESX-1 secretion system protein EccCa1 (eccCa1); Recombinant ESX-1 secretion system protein EccCa1 (eccCa1); ESX-1 secretion system protein EccCa1; ESX conserved component Ca1 Type VII secretion system protein EccCa1; T7SS protein EccCa1; eccCa1 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-747
Sequence
MTTKKFTPTITRGPRLTPGEISLTPPDDLGIDIPPSGVQKILPYVMGGAMLGMIAIMVAGGTRQLSPYMLMMPLMMIVMMVGGLAGSTGGGGKKVPEINADRKEYLRYLAGLRTRVTSSATSQVAFFSYHAPHPEDLLSIVGTQRQWSRPANADFYAATRIGIGDQPAVDRLLKPAVGGELAAASAAPQPFLEPVSHMWVVKFLRTHGLIHDCPKLLQLRTFPTIAIGGDLAGAAGLMTAMICHLAVFHPPDLLQIRVLTEEPDDPDWSWLKWLPHVQHQTETDAAGSTRLIFTRQEGLSDLAARGPHAPDSLPGGPYVVVVDLTGGKAGFPPDGRAGVTVITLGNHRGSAYRIRVHEDGTADDRLPNQSFRQVTSVTDRMSPQQASRIARKLAGWSITGTILDKTSRVQKKVATDWHQLVGAQSVEEITPSRWRMYTDTDRDRLKIPFGHELKTGNVMYLDIKEGAEFGAGPHGMLIGTTGSGKSEFLRTLILSLVAMTHPDQVNLLLTDFKGGSTFLGMEKLPHTAAVVTNMAEEAELVSRMGEVLTGELDRRQSILRQAGMKVGAAGALSGVAEYEKYRERGADLPPLPTLFVVVDEFAELLQSHPDFIGLFDRICRVGRSLRVHLLLATQSLQTGGVRIDKLEPNLTYRIALRTTSSHESKAVIGTPEAQYITNKESGVGFLRVGMEDPVKFSTFYISGPYMPPAAGVETNGEAGGPGQQTTRQAARIHRFTAAPVLEEAPTP
Sequence Length
747
Species
Mycobacterium tuberculosis
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
80,913 Da
NCBI Official Full Name
transmembrane protein
UniProt Protein Name
ESX-1 secretion system protein EccCa1
UniProt Gene Name
eccCa1
UniProt Synonym Gene Names
snm1; T7SS protein EccCa1
UniProt Entry Name
ECC1A_MYCTU

Uniprot Description

Function: Part of a complex that is involved in secretion of ESX-1 substrates, such as EsxA (ESAT-6) and EsxB (CFP-10). Responsible for multiple suppressive effects on macrophages and required for bacterial replication after phagocytosis. Ref.3 Ref.4

Subunit structure: Part of the ESX-1 / type VII secretion system (T7SS), which is composed of cytosolic and membrane components. Interacts with EccCb1. Ref.3

Subcellular location: Cell membrane; Multi-pass membrane protein

Potential.

Disruption phenotype: Disruption abolishes EsxA and EsxB secretion, which results in a lack of antigen specific immunogenicity and leads to attenuated virulence. Does not affect their expression. Ref.3 Ref.4

Miscellaneous: In ESX-1 cluster, the FtsK/SpoIIIE-like protein is split in two genes.

Sequence similarities: Contains 1 FtsK domain.

Similar Products

Product Notes

The ESX-1 secretion system protein EccCa1 (eccCa1) eccca1 (Catalog #AAA1176763) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-747. The amino acid sequence is listed below: MTTKKFTPTI TRGPRLTPGE ISLTPPDDLG IDIPPSGVQK ILPYVMGGAM LGMIAIMVAG GTRQLSPYML MMPLMMIVMM VGGLAGSTGG GGKKVPEINA DRKEYLRYLA GLRTRVTSSA TSQVAFFSYH APHPEDLLSI VGTQRQWSRP ANADFYAATR IGIGDQPAVD RLLKPAVGGE LAAASAAPQP FLEPVSHMWV VKFLRTHGLI HDCPKLLQLR TFPTIAIGGD LAGAAGLMTA MICHLAVFHP PDLLQIRVLT EEPDDPDWSW LKWLPHVQHQ TETDAAGSTR LIFTRQEGLS DLAARGPHAP DSLPGGPYVV VVDLTGGKAG FPPDGRAGVT VITLGNHRGS AYRIRVHEDG TADDRLPNQS FRQVTSVTDR MSPQQASRIA RKLAGWSITG TILDKTSRVQ KKVATDWHQL VGAQSVEEIT PSRWRMYTDT DRDRLKIPFG HELKTGNVMY LDIKEGAEFG AGPHGMLIGT TGSGKSEFLR TLILSLVAMT HPDQVNLLLT DFKGGSTFLG MEKLPHTAAV VTNMAEEAEL VSRMGEVLTG ELDRRQSILR QAGMKVGAAG ALSGVAEYEK YRERGADLPP LPTLFVVVDE FAELLQSHPD FIGLFDRICR VGRSLRVHLL LATQSLQTGG VRIDKLEPNL TYRIALRTTS SHESKAVIGT PEAQYITNKE SGVGFLRVGM EDPVKFSTFY ISGPYMPPAA GVETNGEAGG PGQQTTRQAA RIHRFTAAPV LEEAPTP. It is sometimes possible for the material contained within the vial of "ESX-1 secretion system protein EccCa1 (eccCa1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.