Mouse E4F transcription factor 1 ELISA Kit | E4F1 elisa kit
Mouse Transcription factor E4F1, E4F1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the GLI-Kruppel zinc finger family. The encoded protein is likely to be multi-functional, with both adenovirus E1A-regulated transcription factor and ubiquitin E3 ligase activities, including roles in cell cycle regulation and the ubiquitination of p53. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Uniprot Description
E4F1: May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription.
Protein type: C2H2-type zinc finger protein; EC 6.3.2.-; Ligase; Transcription factor; DNA-binding
Cellular Component: nucleoplasm; cytoplasm; spindle; nucleus
Molecular Function: protein binding; nucleic acid binding; DNA binding; coenzyme F420-2 alpha-glutamyl ligase activity; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity; metal ion binding; ribosomal S6-glutamic acid ligase activity; coenzyme F420-0 gamma-glutamyl ligase activity; ligase activity
Biological Process: mitosis; embryonic development; regulation of mitotic cell cycle, embryonic; transcription, DNA-dependent; regulation of transcription, DNA-dependent; cell division; regulation of growth; negative regulation of transcription from RNA polymerase II promoter; cell cycle; DNA replication
Research Articles on E4F1
Similar Products
Product Notes
The Mouse E4F1 e4f1 (Catalog #AAA9324105) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9324105 ELISA Kit recognizes Mouse E4F1. It is sometimes possible for the material contained within the vial of "E4F transcription factor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
