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Beta Defensin -3 Active Protein | rBD 3 active protein

Recombinant Rat Beta Defensin -3

Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Beta Defensin -3; Recombinant Rat Beta Defensin -3; BD 3 Rat; Beta Defensin-3 Rat Recombinant; Beta-defensin 3; BD-3; Defensin beta 3; Defb3; rBD 3 active protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
BD-3 protein was lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
KKVYNAVSCM TNGGICWLKC SGTFREIGSC GTRQLKCCKK K
Sequence Length
63
Solubility
It is recommended to reconstitute the lyophilized BD-3 in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
Measured by its antimicrobial activity against E. coli. The ED50 for this effect is typically 4-20 ug/ml, corresponding to a specific activity of 50,000-250,000units/mg.
Preparation and Storage
Lyophilized BD-3 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution BD-3 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Related Product Information for rBD 3 active protein
Description: BD-3 Rat Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 41 amino acids and having a molecular mass of 4.5kDa.The BD-3 is purified by proprietary chromatographic techniques.

Introduction: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103A, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.
Product Categories/Family for rBD 3 active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
7,082 Da
NCBI Official Full Name
beta-defensin 3
NCBI Official Synonym Full Names
beta-defensin 3
NCBI Official Symbol
Defb3
NCBI Protein Information
beta-defensin 3; BD-3; defensin, beta 3
UniProt Protein Name
Beta-defensin 3
UniProt Gene Name
Defb3
UniProt Synonym Gene Names
BD-3
UniProt Entry Name
DEFB3_RAT

Uniprot Description

Has bactericidal activity.

Research Articles on rBD 3

Similar Products

Product Notes

The rBD 3 defb3 (Catalog #AAA144401) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: KKVYNAVSCM TNGGICWLKC SGTFREIGSC GTRQLKCCKK K. It is sometimes possible for the material contained within the vial of "Beta Defensin -3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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