GRO/KC (CXCL1) active protein
Rat GRO/KC (CXCL1)
Gene Names
Cxcl1; Gro1; CINC-1
Reactivity
Rat
Purity
> 98% (SDS-PAGE; HPLC)
Synonyms
GRO/KC (CXCL1); Rat GRO/KC (CXCL1); Recombinant Rat GRO/KC; GRO/KC (CXCL1) active protein
Host
E Coli
Reactivity
Rat
Purity/Purification
> 98% (SDS-PAGE; HPLC)
Form/Format
Lyophilized
Sequence
APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKN GREA CLDPEAPMVQ KIVQKMLKGV PK
Sequence Length
96
Endotoxin Level
< 0.1 ng/ug of GRO
Biological Activity
Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.
Related Product Information for GRO/KC (CXCL1) active protein
All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the \'ELR\' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Product Categories/Family for GRO/KC (CXCL1) active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
8.0 kDa
NCBI Official Full Name
growth-regulated alpha protein
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 1
NCBI Official Symbol
Cxcl1
NCBI Official Synonym Symbols
Gro1; CINC-1
NCBI Protein Information
growth-regulated alpha protein; C-X-C motif chemokine 1; cytokine-induced neutrophil chemoattractant 1; platelet-derived growth factor-inducible protein KC; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
UniProt Protein Name
Growth-regulated alpha protein
UniProt Gene Name
Cxcl1
UniProt Synonym Gene Names
Cinc1; Gro; Scyb1; CINC-1
UniProt Entry Name
GROA_RAT
NCBI Description
acts as a neutrophil chemoattractant; may play a role in acute phase inflammatory response [RGD, Feb 2006]
Uniprot Description
Function: Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation.
Subunit structure: Monomer and homodimer.
Subcellular location: Secreted.
Tissue specificity: At least expressed in the lung and trachea.
Induction: By lipopolysaccharides (LPS) and inflammation.
Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.
Research Articles on GRO/KC (CXCL1)
Similar Products
Product Notes
The GRO/KC (CXCL1) cxcl1 (Catalog #AAA691984) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Rat GRO/KC (CXCL1) reacts with Rat and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKN GREA CLDPEAPMVQ KIVQKMLKGV PK. It is sometimes possible for the material contained within the vial of "GRO/KC (CXCL1), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
