Testing Data
IL-2 active protein
Rat IL-2
Reactivity
Species Reactivity: RatCross Reactivity: Mouse
Purity
Above 98% as determined by SDS-PAGE Analysis.
Synonyms
IL-2; Rat IL-2; Recombinant Rat IL-2; IL-2 active protein
Host
E Coli
Reactivity
Species Reactivity: Rat
Cross Reactivity: Mouse
Cross Reactivity: Mouse
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Sequence
MAPTSSPAK ETQQHLEQL LLDLQVLLR GIDNYKNLK LPMMLTFKF YLPKQATEL KHLQCLENE LGALQRVLD LTQSKSFHL EDAGNFISN IRVTVVKLK GSENKFECQ FDDEPATVV EFLRRWIAI AQSIISTM
Biological Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is < 0.4 ng/ml, corresponding to a specific activity of > 2.5 x 106 units/mg.
Cell Type
B Cells, Monocytes and Macrophages, NK and NKT Cells, T Cells, Treg cells
Preparation and Storage
At -20 degree C
Testing Data
Testing Data
Related Product Information for IL-2 active protein
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant rat IL-2 ƒ is a 15.3 kDa protein containing 134 amino acid residues.
Product Categories/Family for IL-2 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
17,633 Da
NCBI Official Full Name
Interleukin-2
NCBI Official Synonym Full Names
interleukin 2
NCBI Official Symbol
Il2
NCBI Protein Information
interleukin-2; IL-2; TCGF; T-cell growth factor
UniProt Protein Name
Interleukin-2
UniProt Gene Name
Il2
UniProt Synonym Gene Names
Il-2; IL-2; TCGF
UniProt Entry Name
IL2_RAT
NCBI Description
cytokine produced by T-cells in response to antigen or mitogen stimulation [RGD, Feb 2006]
Uniprot Description
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
Research Articles on IL-2
Similar Products
Product Notes
The IL-2 il2 (Catalog #AAA696190) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Rat IL-2 reacts with Species Reactivity: Rat Cross Reactivity: Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MAPTSSPAK ETQQHLEQL LLDLQVLLR GIDNYKNLK LPMMLTFKF YLPKQATEL KHLQCLENE LGALQRVLD LTQSKSFHL EDAGNFISN IRVTVVKLK GSENKFECQ FDDEPATVV EFLRRWIAI AQSIISTM. It is sometimes possible for the material contained within the vial of "IL-2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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