Eotaxin-2 Active Protein | Ccl24 active protein
Mouse Eotaxin-2
Gene Names
Ccl24; CKb-6; MPIF-2; Scya24
Reactivity
Mouse
Purity
> 98% by SDS-PAGE and HPLC
Synonyms
Eotaxin-2; Mouse Eotaxin-2; Recombinant Murine Eotaxin-2; Ccl24 active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE and HPLC
Form/Format
Lyophilized
Sequence
VTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHK ICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS T EV
Sequence Length
119
Endotoxin Level
< 0.1 ng per ug of Eotaxin-2
Biological Activity
Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10-100 ng/ml
Related Product Information for Ccl24 active protein
Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant murine Eotaxin-2 is an 10.3 kDa protein containing 93 amino acid residues.
Product Categories/Family for Ccl24 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10.3 kDa
NCBI Official Full Name
C-C motif chemokine 24
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 24
NCBI Official Symbol
Ccl24
NCBI Official Synonym Symbols
CKb-6; MPIF-2; Scya24
NCBI Protein Information
C-C motif chemokine 24; eotaxin-2; CC chemokine CCL24; small inducible cytokine A24; small-inducible cytokine A24; eosinophil chemotactic protein 2
UniProt Protein Name
C-C motif chemokine 24
Protein Family
UniProt Gene Name
Ccl24
UniProt Synonym Gene Names
Scya24
UniProt Entry Name
CCL24_MOUSE
Uniprot Description
Function: Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Binds to CCR3
By similarity.
Subcellular location: Secreted.
Tissue specificity: Highest expression in jejunum and spleen. Lower levels found in liver and lung. No expression detected in kidney, thymus, brain or testis. Ref.2
Induction: By interleukin-4 and allergen challenge with A.fumigatus. Ref.2
Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.
Research Articles on Ccl24
Similar Products
Product Notes
The Ccl24 ccl24 (Catalog #AAA691652) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse Eotaxin-2 reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: VTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHK ICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS T EV. It is sometimes possible for the material contained within the vial of "Eotaxin-2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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