Monocyte Chemotactic Protein-3 Active Protein | mMCP 3 active protein
Recombinant Mouse Monocyte Chemotactic Protein-3 (CCL7)
Gene Names
Ccl7; fic; marc; mcp3; MCP-3; Scya7
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Monocyte Chemotactic Protein-3; Recombinant Mouse Monocyte Chemotactic Protein-3 (CCL7); MCP 3 Mouse; Monocyte Chemotactic Protein-3 Mouse Recombinant (CCL7); Small inducible cytokine A7; CCL7; Monocyte chemotactic protein 3; MCP-3; Monocyte chemoattractant protein 3; NC28; chemokine (C-C motif) ligand 7; FIC; MARC; MCP3; SCYA6; SCYA7; MGC138463; MGC138465; mMCP 3 active protein
Host
E Coli
Purity/Purification
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
The protein was lyophilized from a concentrated (1mg/ml) sterile solution containing no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP
Sequence Length
97
Solubility
It is recommended to reconstitute the lyophilized Monocyte Chemotactic Protein-3 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
The specific activity as determined by the ability of Mouse MCP-3 to chemoattract Balb/C mouse spleen MNCs at 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.
Preparation and Storage
Lyophilized MCP-3 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CCL7should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Related Product Information for mMCP 3 active protein
Description: Monocyte Chemotactic Protein-3 Mouse Recombinant produced in E Coli is a non-glycosylated, Polypeptide chain containing 74 amino acids and having a molecular mass of 8510 Dalton. The MCP-3 is purified by proprietary chromatographic techniques.
Introduction: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). Due to CCL7 possessing two adjacent N-terminal cysteine residues in its mature protein, it is classified among the subfamily of chemokines known as CC chemokines. CCL7 specifically attracts monocytes, and regulates macrophage function. It is produced by certain tumor cell lines and by macrophages. This chemokine is located on chromosome 17 in humans, in a large cluster containing many other CC chemokines and is most closely related to CCL2(previously called MCP1).
Introduction: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). Due to CCL7 possessing two adjacent N-terminal cysteine residues in its mature protein, it is classified among the subfamily of chemokines known as CC chemokines. CCL7 specifically attracts monocytes, and regulates macrophage function. It is produced by certain tumor cell lines and by macrophages. This chemokine is located on chromosome 17 in humans, in a large cluster containing many other CC chemokines and is most closely related to CCL2(previously called MCP1).
Product Categories/Family for mMCP 3 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,999 Da
NCBI Official Full Name
C-C motif chemokine 7
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 7
NCBI Official Symbol
Ccl7
NCBI Official Synonym Symbols
fic; marc; mcp3; MCP-3; Scya7
NCBI Protein Information
C-C motif chemokine 7; RANTES/sis homolog; intercrine/chemokine MARC; monocyte chemoattractant protein 3; monocyte chemotactic protein 3; small inducible cytokine A7; small-inducible cytokine A7
UniProt Protein Name
C-C motif chemokine 7
UniProt Gene Name
Ccl7
UniProt Synonym Gene Names
Fic; Mcp3; Scya7; MCP-3
UniProt Entry Name
CCL7_MOUSE
Uniprot Description
CCL7: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Cellular Component: extracellular space; extracellular region
Molecular Function: heparin binding; CCR2 chemokine receptor binding; chemokine activity; cytokine activity
Biological Process: immune response; chemotaxis; inflammatory response
Research Articles on mMCP 3
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Product Notes
The mMCP 3 ccl7 (Catalog #AAA142027) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP. It is sometimes possible for the material contained within the vial of "Monocyte Chemotactic Protein-3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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