RELM beta active protein
Human RELM beta
Gene Names
RETNLB; XCP2; FIZZ1; FIZZ2; HXCP2; RELMb; RELMbeta; RELM-beta
Reactivity
Human
Purity
> 97% by SDS-PAGE and HPLC analysis
Synonyms
RELM beta; Human RELM beta; Recombinant Human RELM-beta; RELM beta active protein
Host
E Coli
Reactivity
Human
Purity/Purification
> 97% by SDS-PAGE and HPLC analysis
Form/Format
Lyophilized
Sequence
MQCSLDSVMDKKIKDVLNSLEYSPSPISKKLSCASVKSQGRPSSCPAGMA VTGCACGYGCGSWDVQLETTCHCQCSVVDWTTARCCHLT
Sequence Length
111
Endotoxin Level
< 0.1 ng per ug of RELM-beta
Biological Activity
Data not available.
Related Product Information for RELM beta active protein
Human RELM beta is a 19.0 kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELM beta, and its molecular targets, are not fully known but, it has been suggested that it plays a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly the molecular structure of RELM beta is highly homologous to that of the adipose-derived cytokine Resistin and RELMa. These proteins share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Recombinant human RELM beta is a 19.0 kDa homodimer consisting of two identical 89 amino acid chains linked by a single disulfide bond.
Product Categories/Family for RELM beta active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19 kDa
NCBI Official Full Name
resistin-like beta
NCBI Official Synonym Full Names
resistin like beta
NCBI Official Symbol
RETNLB
NCBI Official Synonym Symbols
XCP2; FIZZ1; FIZZ2; HXCP2; RELMb; RELMbeta; RELM-beta
NCBI Protein Information
resistin-like beta; found in inflammatory zone 1; colon carcinoma-related gene protein; cysteine-rich secreted protein FIZZ2; cysteine-rich secreted A12-alpha-like protein 1; cysteine-rich secreted protein A12-alpha-like 1; colon and small intestine-specific cysteine-rich protein; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 2
UniProt Protein Name
Resistin-like beta
UniProt Gene Name
RETNLB
UniProt Synonym Gene Names
CCRG; FIZZ2; HXCP2; RETNL2
UniProt Entry Name
RETNB_HUMAN
Uniprot Description
Function: Probable hormone.
Subunit structure: Homodimer; disulfide-linked
By similarity.
Subcellular location: Secreted.
Tissue specificity: Expressed only in the gastrointestinal tract, particularly the colon.
Sequence similarities: Belongs to the resistin/FIZZ family.
Research Articles on RELM beta
Similar Products
Product Notes
The RELM beta retnlb (Catalog #AAA691595) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human RELM beta reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MQCSLDSVMD KKIKDVLNSL EYSPSPISKK LSCASVKSQG RPSSCPAGMA VTGCACGYGC GSWDVQLETT CHCQCSVVDW TTARCCHLT. It is sometimes possible for the material contained within the vial of "RELM beta, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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