NT-3 active protein
Human NT-3
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Seems to promote the survival of visceral and proprioceptive sensory neurons.
Subcellular location: Secreted.
Tissue specificity: Brain and peripheral tissues.
Polymorphism: Variant Glu-76 (frequently reported as Glu-63) was thought to be associated with severe forms of schizophrenia. This does not seem to be the case.
Sequence similarities: Belongs to the NGF-beta family.
Research Articles on NT-3
Similar Products
Product Notes
The NT-3 ntf3 (Catalog #AAA691786) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human NT-3 reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGN SPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL T SENNKLVGW RWIRIDTSCV CALSRKIGRT. It is sometimes possible for the material contained within the vial of "NT-3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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