Fractalkine (CX3CL1) Active Protein | CX3CL1 active protein
Human Fractalkine (CX3CL1)
NCBI and Uniprot Product Information
Uniprot Description
Function: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. Ref.8
Subunit structure: Monomer. Interacts with pox virus crmD; this inhibits cell migration mediated by CX3CL1. Ref.6 Ref.8
Subcellular location: Cell membrane; Single-pass type I membrane protein. Processed fractalkine: Secreted.
Tissue specificity: Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
Induction: By TNF and IL1/interleukin-1 in pulmonary endothelial cells and umbilical vein endothelial cells.
Post-translational modification: A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form
By similarity.O-glycosylated with core 1 or possibly core 8 glycans. Ref.5
Sequence similarities: Belongs to the intercrine delta family.
Research Articles on CX3CL1
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Product Notes
The CX3CL1 cx3cl1 (Catalog #AAA692067) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human Fractalkine (CX3CL1) reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQH RLFC ADPKEQWVKD AMQHLDRQAA ALTRNG. It is sometimes possible for the material contained within the vial of "Fractalkine (CX3CL1), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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