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N-acetylgalactosamine-6-sulfatase Protein | GALNS protein

N-acetylgalactosamine-6-sulfatase

Gene Names
GALNS; GAS; MPS4A; GalN6S; GALNAC6S
Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
N-acetylgalactosamine-6-sulfatase; Chondroitinsulfatase; Galactose-6-sulfate sulfatase; N-acetylgalactosamine-6-sulfate sulfatase; Chondroitinase; GalN6S; GalNAc6S sulfatase; GALNS protein
Ordering
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid
Sequence Length
522
Applicable Applications for GALNS protein
ELISA (EIA), Western Blot (WB), Affinity Purification (AP), Protein Array
Tags
His
Storage Buffer
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Preparation and Storage
Store at -20 degree C.
Avoid repeated freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
58,026 Da
NCBI Official Full Name
N-acetylgalactosamine-6-sulfatase isoform 1
NCBI Official Synonym Full Names
galactosamine (N-acetyl)-6-sulfatase
NCBI Official Symbol
GALNS
NCBI Official Synonym Symbols
GAS; MPS4A; GalN6S; GALNAC6S
NCBI Protein Information
N-acetylgalactosamine-6-sulfatase
UniProt Protein Name
N-acetylgalactosamine-6-sulfatase
UniProt Gene Name
GALNS
UniProt Synonym Gene Names
Chondroitinase; GalN6S; GalNAc6S sulfatase

NCBI Description

This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq, Jul 2008]

Research Articles on GALNS

Similar Products

Product Notes

The GALNS galns (Catalog #AAA2888601) is a Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's N-acetylgalactosamine-6-sulfatase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Affinity Purification (AP), Protein Array. Researchers should empirically determine the suitability of the GALNS galns for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "N-acetylgalactosamine-6-sulfatase, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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