Serine Protease Inhibitor-Clade F1 Active Protein | Serpinf1 active protein
Recombinant Mouse Serine Protease Inhibitor-Clade F1 Protein
Gene Names
Serpinf1; Pedf; Sdf3; EPC-1; Pedfl; AI195227
Purity
>95% as determined by SDS-PAGE
Synonyms
Serine Protease Inhibitor-Clade F1; Recombinant Mouse Serine Protease Inhibitor-Clade F1 Protein; Pigment epithelium-derived factor; Pedf; Sdf3; Caspin; Serpin F1; Stromal cell-derived factor 3.; Serpinf1 active protein
Host
E Coli
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Sequence
Asp43-Thr417
Sequence Length
417
Species
Mouse
Endotoxin
< 1.0 EU per mug as determined by the LAL method.
Activity
Measured by its binding ability in a functional ELISA.Immobilized mouse SERPINF1-His at 10 mug/ml (100 mul/well) can bind biotinylated human GST-CSNK2A1 with a linear range of 0.31-2.5 mug/ml.
Preparation and Storage
Store at < -20 degree C, stable for 6 months. Please minimize freeze-thaw cycles.
Related Product Information for Serpinf1 active protein
Protein Construction: Recombinant Mouse Serine Protease Inhibitor-clade F1 is produced by our E Coli expression system and the target gene encoding Asp43-Thr417 is expressed.
Background: Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity.
Background: Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 42.0kDa
Actual Protein Molecular Mass: 40kDa
Actual Protein Molecular Mass: 40kDa
NCBI Official Full Name
pigment epithelium-derived factor
NCBI Official Synonym Full Names
serine (or cysteine) peptidase inhibitor, clade F, member 1
NCBI Official Symbol
Serpinf1
NCBI Official Synonym Symbols
Pedf; Sdf3; EPC-1; Pedfl; AI195227
NCBI Protein Information
pigment epithelium-derived factor
UniProt Protein Name
Pigment epithelium-derived factor
Protein Family
UniProt Gene Name
Serpinf1
UniProt Synonym Gene Names
Pedf; Sdf3; PEDF; SDF-3
Uniprot Description
Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Research Articles on Serpinf1
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Product Notes
The Serpinf1 serpinf1 (Catalog #AAA2557418) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Asp43-Thr4 17. It is sometimes possible for the material contained within the vial of "Serine Protease Inhibitor-Clade F1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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