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Myostatin Fusion Protein Active Protein

Myostatin Fusion Protein, Recombinant, Human (Lyophilized) (Growth Differentiation Factor 8, MSTN, gdf8)

Purity
Affinity Purified
98% by SDS-PAGE and HPLC analyses. Endotoxin:
Synonyms
Myostatin Fusion Protein; Recombinant; Human (Lyophilized) (Growth Differentiation Factor 8; MSTN; gdf8); Myostatin Fusion Protein active protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Affinity Purified
98% by SDS-PAGE and HPLC analyses. Endotoxin:
Form/Format
Supplied as a lyophilized powder. Reconstitute in sterile 10mM Acetic acid to 0.1-1.0mg/ml. Do not vortex. Add carrier protein for long term storage
Sequence
DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS
Biological Activity
Determined by its ability to inhibit the proliferation of MPC-11 cells. The expected ED50 for this effect is 17-25ng/ml.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with acetic acid. Add carrier protein for long term storage. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Myostatin Fusion Protein active protein
Myostatin is a TGF-beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin.

Recombinant Human myostatin is a 25kD protein consisting of two identical 109 amino acid polypeptides linked by a single disulfide bond.
Product Categories/Family for Myostatin Fusion Protein active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
myostatin, partial

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Product Notes

The Myostatin Fusion Protein (Catalog #AAA650846) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS. It is sometimes possible for the material contained within the vial of "Myostatin Fusion Protein, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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